Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 7/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28810272 | 0.94 | TSHR (0.49) | ALDH1A1BCHETSHRL3MBTL1TDP1 | |
| SCHEMBL23953095 | 0.88 | ALDH1A1 (0.44) | ALDH1A1BCHETSHRL3MBTL1TDP1 | |
| SCHEMBL27810242 | 0.79 | ALDH1A1 (0.42) | ALDH1A1BCHETSHRL3MBTL1LMNA | |
| SCHEMBL30403372 | 0.77 | TSHR (0.53) | ALDH1A1BCHETSHRL3MBTL1TDP1 | |
| SCHEMBL943943 | 0.77 | SMN1; SMN2 (0.44) | ALDH1A1BCHETSHRL3MBTL1TDP1 | |
| SCHEMBL28030479 | 0.75 | ESR1 (0.49) | ALDH1A1BCHETSHRL3MBTL1TDP1 | |
| SCHEMBL27295005 | 0.73 | MEN1 (0.54) | ALDH1A1TSHRL3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL4566478 | 0.73 | NOS1 (0.46) | ALDH1A1BCHETSHRL3MBTL1TDP1 | |
| SCHEMBL4780587 | 0.73 | LMNA (0.44) | ALDH1A1BCHETSHRL3MBTL1TDP1 | |
| SCHEMBL164228 | 0.72 | BCHE (0.51) | ALDH1A1BCHETSHRL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325041-A1 | Lithium Secondary Battery | HITACHI, LTD. (JP) | 2009-12-31 | — | — | US | disclosed |
| CN-1980660-A | Contraceptive regimens and kits for progesterone receptor antagonists | WYETH CORP (US) | 2007-06-13 | — | — | CN | disclosed |
| EP-1351684-A4 | COMPOUNDS AND METHODS FOR PROMOTING SMOKING CESSATION | RES TRIANGLE INST (US) | 2005-01-19 | — | — | EP | disclosed |
| WO-2005000806-A2 | LIGANDS FOR NICOTINIC ACETYLCHOLINE RECEPTORS, AND METHODS OF MAKING AND USING THEM | GEORGETOWN UNIVERSITY (US) | 2005-01-06 | — | — | WO | disclosed |
| WO-2004099373-A2 | BIOCOMPATIBLE RESISTS | UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2004-11-18 | — | — | WO | disclosed |
| EP-1351684-A2 | COMPOUNDS AND METHODS FOR PROMOTING SMOKING CESSATION | Research Triangle Institute (US) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002037927-A2 | COMPOUNDS AND METHODS FOR PROMOTING SMOKING CESSATION | RESEARCH TRIANGLE INSTITUTE (US) | 2002-05-16 | — | — | WO | disclosed |
| US-6384228-B2 | EPIBATIDINE; ANALGESICS; ANIMAL EXTRACTS | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| US-20020010339-A1 | METHOD FOR SYNTHESIS OF HALOPYRIDYL-ACYCLOPENTANE DERIVATIVE AND INTERMEDIATE THEREOF | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2002-01-24 | — | — | US | disclosed |
| US-5591854-A | CATALYTIC CONDENSATION OF DIENES AND VINYLDIAZOMETHANEESTERS | WAKE FOREST UNIVERSITY (US) | 1997-01-07 | — | — | US | disclosed |
| WO-1996011928-A1 | ENANTIOSELECTIVE SYNTHESIS OF SEVEN-MEMBERED CARBOCYCLES AND TROPANES | WAKE FOREST UNIVERSITY (US) | 1996-04-25 | — | — | WO | disclosed |
| US-3980089-A | Novel heterocyclic flavoring compositions and processes | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010339-A1 | METHOD FOR SYNTHESIS OF HALOPYRIDYL-ACYCLOPENTANE DERIVATIVE AND INTERMEDIATE THEREOF | DHPS, ALAD, HAAO | ALDH1A1 242/4885BCHE 2731/4885TSHR 4144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.