Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458110 | 0.86 | TP53 (0.31) | — | |
| SCHEMBL455217 | 0.81 | SHMT2 (0.32) | HPGDSMN1; SMN2L3MBTL1KDM4ENPC1 | |
| SCHEMBL455470 | 0.81 | HPGD (0.32) | HPGDSMN1; SMN2L3MBTL1KDM4ENPC1 | |
| SCHEMBL457003 | 0.69 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL456779 | 0.69 | TP53 (0.31) | — | |
| SCHEMBL3982745 | 0.69 | ALDH1A1 (0.47) | L3MBTL1KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL23260378 | 0.63 | PTPN1 (0.33) | KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL21625337 | 0.62 | NPC1 (0.45) | HPGDSMN1; SMN2L3MBTL1KDM4ENPC1 | |
| SCHEMBL455737 | 0.62 | CYP1A2 (0.33) | ALDH1A1 | |
| SCHEMBL4661765 | 0.61 | CTSK (0.35) | HPGDSMN1; SMN2L3MBTL1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |