Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEH1 | O60930 | 2/20 | 0.51 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.51 |
| ▸ | FEN1 | P39748 | 2/20 | 0.51 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11396560 | 0.77 | LTB4R (0.44) | ALDH1A1HPGDHSD17B10KDM4EGAA | |
| SCHEMBL12487639 | 0.76 | SMN1; SMN2 (0.47) | RNASEH1ERCC1FEN1ERCC4TNKS | |
| SCHEMBL10727938 | 0.75 | LTB4R (0.61) | TNKSPARP1TNKS2SMN1; SMN2ALDH1A1 | |
| SCHEMBL468691 | 0.74 | LTB4R (0.47) | ALDH1A1HPGDHSD17B10KDM4EGAA | |
| SCHEMBL24087904 | 0.72 | ACMSD (0.56) | SMN1; SMN2ALDH1A1HPGDKDM4EHTT | |
| SCHEMBL8764478 | 0.72 | PIN1 (0.50) | SMN1; SMN2ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL4879388 | 0.72 | LTB4R (0.45) | SMN1; SMN2ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL4879384 | 0.70 | LTB4R (0.40) | ADORA3SMN1; SMN2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL22372656 | 0.69 | POLB (0.62) | RNASEH1ERCC1FEN1ERCC4TNKS | |
| SCHEMBL10338070 | 0.69 | ERCC1 (0.55) | RNASEH1ERCC1FEN1ERCC4TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2475654-A1 | HERBICIDAL PYRIMIDONE DERIVATIVES | E. I. du Pont de Nemours and Company (US) | 2012-07-18 | — | — | EP | disclosed |
| WO-2012033548-A2 | HERBICIDAL BIS-NITROGEN-CONTAINING OXO AND SULFONO HETEROCYCLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-15 | — | — | WO | disclosed |
| WO-2011031658-A1 | HERBICIDAL PYRIMIDONE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-17 | — | — | WO | disclosed |