SCHEMBL4568670

SCHEMBL4568670

COc1ccc(C2(c3ccc(OC)cc3)C=Cc3c4c(c5cc(N6CCOCC6)c(SC)cc5c3O2)-c2ccccc2C42CC(C)(C)CC(C)(C)C2)cc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.30
PRKDC P78527 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16300306 1.00 POLB (0.30) POLBPRKDC
SCHEMBL16300286 0.94 AKT1 (0.31) PRKDC
SCHEMBL4568666 0.94
SCHEMBL15458557 0.92
SCHEMBL15459689 0.92
SCHEMBL15459719 0.92
SCHEMBL15452315 0.91 PRKDC (0.33) PRKDC
SCHEMBL15763599 0.90 POLB (0.30) POLBPRKDC
SCHEMBL15763649 0.90 POLB (0.30) POLBPRKDC
SCHEMBL15458486 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9447224-B2 Urethane (meth) acrylate monomer and production process thereof TOKUYAMA CORPORATION (JP) 2016-09-20 US disclosed
US-9447224-B2 Urethane (meth) acrylate monomer and production process thereof TOKUYAMA CORPORATION (JP) 2016-09-20 US disclosed
US-8308996-B2 Chromene compound TOKUYAMA CORPORATION (JP) 2012-11-13 US disclosed
US-8308996-B2 Chromene compound TOKUYAMA CORPORATION (JP) 2012-11-13 US disclosed
EP-2502945-A1 URETHANE (METH) ACRYLATE MONOMER AND MANUFACTURING METHOD FOR SAME Tokuyama Corporation (JP) 2012-09-26 EP disclosed
US-20120228567-A1 URETHANE (METH) ACRYLATE MONOMER AND PRODUCTION PROCESS THEREOF TOKUYAMA CORPORATION (JP) 2012-09-13 US disclosed
US-20120228567-A1 URETHANE (METH) ACRYLATE MONOMER AND PRODUCTION PROCESS THEREOF TOKUYAMA CORPORATION (JP) 2012-09-13 US disclosed
US-20120121934-A1 CHROMENE COMPOUND TOKUYAMA CORPORATION (JP) 2012-05-17 US disclosed
US-20120121934-A1 CHROMENE COMPOUND TOKUYAMA CORPORATION (JP) 2012-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120228567-A1 URETHANE (METH) ACRYLATE MONOMER AND PRODUCTION PROCESS THEREOF MTDH, PAM, ACR POLB 1440/4885PRKDC 1038/4885
US-20120121934-A1 CHROMENE COMPOUND TST, CNOT1, CNOT9 POLB 3324/4885PRKDC 2885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.