Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12566547 | 1.00 | P2RX7 (0.30) | P2RX7 | |
| SCHEMBL12566879 | 1.00 | P2RX7 (0.30) | P2RX7 | |
| SCHEMBL12546154 | 0.98 | P2RX7 (0.30) | P2RX7 | |
| SCHEMBL18737218 | 0.98 | P2RX7 (0.30) | P2RX7 | |
| SCHEMBL20259597 | 0.98 | P2RX7 (0.30) | P2RX7 | |
| SCHEMBL24677462 | 0.98 | P2RX7 (0.30) | P2RX7 | |
| SCHEMBL20259642 | 0.98 | P2RX7 (0.30) | P2RX7 | |
| SCHEMBL23766519 | 0.98 | P2RX7 (0.30) | P2RX7 | |
| SCHEMBL840278 | 0.98 | P2RX7 (0.30) | P2RX7 | |
| SCHEMBL839891 | 0.93 | AR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105585644-A | Ziegler-Natta catalyst component for olefin polymerization and catalyst thereof | PETROCHINA CO LTD | 2016-05-18 | — | — | CN | claimed |
| EP-0016582-B1 | ZIEGLER-TYPE CATALYST COMPOSITION | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1984-10-03 | — | — | EP | claimed |
| EP-0016581-B1 | ZIEGLER TYPE CATALYST COMPOSITION | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1984-08-08 | — | — | EP | claimed |
| EP-0015763-B1 | ZIEGLER TYPE CATALYST SYSTEM | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1984-05-16 | — | — | EP | claimed |
| EP-0035889-B1 | ALKYL-METAL COCATALYST | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1984-05-02 | — | — | EP | claimed |
| US-20240226113-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2024-07-11 | — | — | US | disclosed |
| WO-2024107763-A1 | N6-ADENOSINE-METHYLTRANSFERASE PROTACS AND METHODS OF USE THEREOF | UNIVERSITY OF ZURICH (CH) | 2024-05-23 | — | — | WO | disclosed |
| US-20240067642-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2024-02-29 | — | — | US | disclosed |
| US-20240067642-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2024-02-29 | — | — | US | disclosed |
| US-20240024318-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2024-01-25 | — | — | US | disclosed |
| US-20240018118-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C 4 Therapeutics, Inc. (US) | 2024-01-18 | — | — | US | disclosed |
| WO-2023247590-A1 | TRIAZOLOPYRIDINE AND BENZOISOXAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | disclosed |
| EP-0344755-B2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1997-09-10 | — | — | EP | disclosed |
| CN-1035385-C | Process for preparing stabilized polyolefins | HIMONT INC (US) | 1997-07-09 | — | — | CN | disclosed |
| CN-1074222-A | Process for preparing stabilized polyolefins and products thereof | HIMONT INC (US) | 1993-07-14 | — | — | CN | disclosed |
| EP-0267576-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF ALPHA-OLEFINS TO STEREOREGULAR POLYMERS HAVING NARROW MOLECULAR WEIGHT DISTRIBUTION | Himont Incorporated (US) | 1992-05-27 | — | — | EP | disclosed |
| EP-0376145-A2 | Method for producing a stereoregular polyolefin | Tosoh Corporation (JP) | 1990-07-04 | — | — | EP | disclosed |
| EP-0373660-A2 | Propylene polymer compositions having good transparency and improved impact resistance | MONTELL NORTH AMERICA INC. (US) | 1990-06-20 | — | — | EP | disclosed |
| EP-0344755-A1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1989-12-06 | — | — | EP | disclosed |
| EP-0267576-A2 | Components and catalysts for the polymerization of alpha-olefins to stereoregular polymers having narrow molecular weight distribution | Himont Incorporated (US) | 1988-05-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240024318-A1 | SMARCA DEGRADERS AND USES THEREOF | SMARCA1, SMARCA2, SMARCC2 | P2RX7 3649/4885 |
| US-20240226113-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | TP53, HRAS, KRAS | P2RX7 3782/4885 |
| US-20240018118-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | NFATC1, CTSS, MMP12 | P2RX7 3896/4885 |
| US-20240067642-A1 | COMPOUNDS AND USES THEREOF | VHL, TFEB, BECN1 | P2RX7 1952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.