Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4553375 | 0.88 | LMNA (0.33) | IRAK4SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL963384 | 0.87 | IRAK4 (0.33) | IRAK4ALDH1A1LMNACYP2C19CYP2D6 | |
| SCHEMBL4570524 | 0.84 | IRAK4 (0.35) | IRAK4MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL963027 | 0.80 | IRAK4 (0.33) | IRAK4ALDH1A1CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL962936 | 0.79 | IRAK4 (0.35) | IRAK4ALDH1A1CYP2C19CYP2C9 | |
| SCHEMBL4554378 | 0.78 | IRAK4 (0.34) | IRAK4MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL962809 | 0.74 | ADAMTS5 (0.35) | IRAK4MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL965265 | 0.74 | ADAMTS5 (0.33) | IRAK4MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL965261 | 0.74 | ADAMTS5 (0.33) | IRAK4MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL962959 | 0.74 | HPGD (0.32) | IRAK4MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118066-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | Takeda Pharmaceutical Company Limited (JP) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008099794-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-08-21 | — | — | WO | disclosed |