Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HPGDS | O60760 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GRN | P28799 | 1/20 | 0.47 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.46 |
| ▸ | ICMT | O60725 | 1/20 | 0.43 |
| ▸ | CLPP | Q16740 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455429 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KMT2AKDM4EPOLBHPGDS | |
| SCHEMBL455428 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KMT2AKDM4EPOLBHPGDS | |
| SCHEMBL9755640 | 0.95 | ALDH1A1 (0.52) | ALDH1A1KMT2AKDM4EPOLBHPGDS | |
| SCHEMBL9755630 | 0.88 | ALDH1A1 (0.50) | ALDH1A1KMT2AKDM4EPOLBHPGDS | |
| SCHEMBL735245 | 0.88 | ALDH1A1 (0.72) | ALDH1A1KMT2AKDM4EPOLBCA1 | |
| SCHEMBL452263 | 0.88 | ALDH1A1 (0.72) | ALDH1A1KMT2AKDM4EPOLBCA1 | |
| SCHEMBL452264 | 0.88 | ALDH1A1 (0.72) | ALDH1A1KMT2AKDM4EPOLBCA1 | |
| SCHEMBL8964497 | 0.85 | TAS1R3 (0.65) | ALDH1A1KMT2AKDM4EPOLBGAA | |
| SCHEMBL8964493 | 0.85 | TAS1R3 (0.65) | ALDH1A1KMT2AKDM4EPOLBGAA | |
| SCHEMBL9755632 | 0.85 | KMT2A (0.43) | ALDH1A1KMT2AKDM4EPOLBHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616169-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | Natrix Separations Inc. (CA) | 2013-07-24 | — | — | EP | claimed |
| WO-2012037101-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | NATRIX SEPARATIONS INC. (CA) | 2012-03-22 | — | — | WO | claimed |
| EP-2616169-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | Natrix Separations Inc. (CA) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012037101-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | NATRIX SEPARATIONS INC. (CA) | 2012-03-22 | — | — | WO | disclosed |
| US-20120064601-A1 | Chromatography Membranes for the Purification of Chiral Compounds | NATRIX SEPARATIONS INC. (CA) | 2012-03-15 | — | — | US | disclosed |