Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | GRN | P28799 | 3/20 | 0.62 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.62 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | ICMT | O60725 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL452264 | 1.00 | ALDH1A1 (0.72) | ALDH1A1KMT2AKDM4EPOLBGRN | |
| SCHEMBL452263 | 1.00 | ALDH1A1 (0.72) | ALDH1A1KMT2AKDM4EPOLBGRN | |
| SCHEMBL7124555 | 0.89 | KMT2A (0.58) | ALDH1A1KMT2AKDM4EPOLBGRN | |
| SCHEMBL457080 | 0.88 | ALDH1A1 (0.56) | ALDH1A1KMT2AKDM4EPOLBGRN | |
| SCHEMBL455428 | 0.88 | ALDH1A1 (0.56) | ALDH1A1KMT2AKDM4EPOLBGRN | |
| SCHEMBL455429 | 0.88 | ALDH1A1 (0.56) | ALDH1A1KMT2AKDM4EPOLBGRN | |
| SCHEMBL8964493 | 0.86 | TAS1R3 (0.65) | ALDH1A1KMT2AKDM4EPOLBGAA | |
| SCHEMBL8964497 | 0.86 | TAS1R3 (0.65) | ALDH1A1KMT2AKDM4EPOLBGAA | |
| SCHEMBL16684621 | 0.86 | ALDH1A1 (0.64) | ALDH1A1KMT2AKDM4EPOLBGRN | |
| SCHEMBL28060524 | 0.85 | ICMT (0.56) | ALDH1A1KMT2AKDM4EPOLBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8137548-B2 | Chelator-modified inorganic oxide particles | ZIRCHROM SEPARATIONS, INC. (US) | 2012-03-20 | — | — | US | disclosed |
| US-20050118409-A1 | Chelator-modified inorganic oxide particles | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-06-02 | — | — | US | disclosed |
| WO-2005037397-A1 | CHELATOR-MODIFIED INORGANIC OXIDE PARTICLES | ZIRCHROM SEPARATIONS, INC. (US) | 2005-04-28 | — | — | WO | disclosed |
| US-20030097002-A1 | Enantioselective reactions using two-component chiral phase transfer catalysts in multiphasic systems | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2003-05-22 | — | — | US | disclosed |
| WO-2002092562-A2 | ENANTIOSELECTIVE REACTIONS USING TWO-COMPONENT CHIRAL PHASE TRANSFER CATALYSTS IN MULTIPHASIC SYSTEMS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2002-11-21 | — | — | WO | disclosed |
| US-4668674-A | ANTIULCER AGENTS | DR. KARL THOMAE GMBH (DE) | 1987-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030097002-A1 | Enantioselective reactions using two-component chiral phase transfer catalysts in multiphasic systems | COASY, MOGAT2, ICMT | ALDH1A1 1743/4885KMT2A 468/4885KDM4E 3273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.