Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | GRN | P28799 | 3/20 | 0.62 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.62 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | ICMT | O60725 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL452264 | 1.00 | ALDH1A1 (0.72) | ALDH1A1KMT2AKDM4EPOLBGRN | |
| SCHEMBL735245 | 1.00 | ALDH1A1 (0.72) | ALDH1A1KMT2AKDM4EPOLBGRN | |
| SCHEMBL7124555 | 0.89 | KMT2A (0.58) | ALDH1A1KMT2AKDM4EPOLBGRN | |
| SCHEMBL457080 | 0.88 | ALDH1A1 (0.56) | ALDH1A1KMT2AKDM4EPOLBGRN | |
| SCHEMBL455428 | 0.88 | ALDH1A1 (0.56) | ALDH1A1KMT2AKDM4EPOLBGRN | |
| SCHEMBL455429 | 0.88 | ALDH1A1 (0.56) | ALDH1A1KMT2AKDM4EPOLBGRN | |
| SCHEMBL8964493 | 0.86 | TAS1R3 (0.65) | ALDH1A1KMT2AKDM4EPOLBGAA | |
| SCHEMBL8964497 | 0.86 | TAS1R3 (0.65) | ALDH1A1KMT2AKDM4EPOLBGAA | |
| SCHEMBL16684621 | 0.86 | ALDH1A1 (0.64) | ALDH1A1KMT2AKDM4EPOLBGRN | |
| SCHEMBL28060524 | 0.85 | ICMT (0.56) | ALDH1A1KMT2AKDM4EPOLBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2018-09-11 | — | — | US | claimed |
| CN-105749890-A | Chiral stationary phase prepared by taking cinchonidine-boc-amide as chiral selector as well as preparation method and application thereof | 河南科技学院 | 2016-07-13 | — | — | CN | claimed |
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | Indiana University Research and Technology Corpora tion (US) | 2016-06-23 | — | — | US | claimed |
| CN-105642261-A | Chiral stationary phase prepared with cinchonine-Boc-amide as chiral selector and preparation method and application thereof | 河南科技学院 | 2016-06-08 | — | — | CN | claimed |
| CN-105561959-A | Chiral stationary phase prepared by taking quinine-tertiary butyl carbamate as a chiral selector and preparation method and application of chiral stationary phase | HENAN INST OF SCIENCE & TECH | 2016-05-11 | — | — | CN | claimed |
| CN-105498736-A | Chiral stationary phase prepared by taking quinindium-t-butyl carbamate as chirality selector as well as preparation method and application of chiral stationary phase | HENAN INST OF SCIENCE & TECH | 2016-04-20 | — | — | CN | claimed |
| US-9217012-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-12-22 | — | — | US | claimed |
| EP-2616169-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | Natrix Separations Inc. (CA) | 2013-07-24 | — | — | EP | claimed |
| US-20120088720-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) | 2012-04-12 | — | — | US | claimed |
| WO-2012037101-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | NATRIX SEPARATIONS INC. (CA) | 2012-03-22 | — | — | WO | claimed |
| US-20120064601-A1 | Chromatography Membranes for the Purification of Chiral Compounds | NATRIX SEPARATIONS INC. (CA) | 2012-03-15 | — | — | US | claimed |
| WO-2010118241-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2010-10-14 | — | — | WO | claimed |
| US-20050118409-A1 | Chelator-modified inorganic oxide particles | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-06-02 | — | — | US | claimed |
| WO-2005037397-A1 | CHELATOR-MODIFIED INORGANIC OXIDE PARTICLES | ZIRCHROM SEPARATIONS, INC. (US) | 2005-04-28 | — | — | WO | claimed |
| EP-0532664-B1 | SUPPORTED CHIRAL LIQUID MEMBRANE FOR THE SEPARATION OF ENANTIOMERS | RES CORP TECHNOLOGIES INC (US) | 1996-02-14 | — | — | EP | claimed |
| US-5422004-A | Monocyclic or polycyclic aromatic amide moiety; increased enantioselectivity | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-06-06 | — | — | US | claimed |
| WO-1994000408-A1 | HIGH PERFORMANCE CHIRAL SELECTOR | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-01-06 | — | — | WO | claimed |
| WO-1993022272-A1 | RECOGNITION AND SEPARATION OF CARBON CLUSTERS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-11-11 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | PTPRCAP, PTPRF, PTPRS | ALDH1A1 3087/4885KMT2A 2681/4885KDM4E 2134/4885 |
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | PTPRCAP, PTPRF, PTPRS | ALDH1A1 3087/4885KMT2A 2681/4885KDM4E 2134/4885 |
| US-20120088720-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | PTPRCAP, PTPRF, PTPRS | ALDH1A1 3087/4885KMT2A 2681/4885KDM4E 2134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.