Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8352830 | 0.85 | — | — | |
| SCHEMBL2288677 | 0.83 | — | — | |
| SCHEMBL2286232 | 0.83 | — | — | |
| SCHEMBL2290855 | 0.83 | — | — | |
| SCHEMBL2283977 | 0.79 | PDE3B (0.35) | — | |
| SCHEMBL2285358 | 0.78 | — | — | |
| SCHEMBL1403694 | 0.74 | KDM4E (0.31) | — | |
| SCHEMBL27560371 | 0.74 | — | — | |
| SCHEMBL27405123 | 0.72 | PTGS2 (0.38) | — | |
| SCHEMBL743996 | 0.71 | GABRA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104955984-B | Sliding member and method for manufacturing same | 日产自动车株式会社 | 2018-06-12 | — | — | CN | disclosed |
| EP-3045450-B1 | INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2018-02-07 | — | — | EP | disclosed |
| EP-3045450-A1 | INTERMEDIATE COMPOUNDS IN A PROCESS FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO., LTD. (JP) | 2016-07-20 | — | — | EP | disclosed |
| EP-2614053-B1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATES THEREOF | SUMITOMO CHEMICAL CO (JP) | 2016-03-23 | — | — | EP | disclosed |
| CN-104955984-A | Sliding member and method for manufacturing same | NISSAN MOTOR | 2015-09-30 | — | — | CN | disclosed |
| US-9040709-B2 | Method for producing pyridazinone compounds and intermediate thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-05-26 | — | — | US | disclosed |
| US-20140378688-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2014-12-25 | — | — | US | disclosed |
| US-8884010-B2 | Method for producing pyridazinone compounds and intermediate thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-11-11 | — | — | US | disclosed |
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| US-20130172556-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-04 | — | — | US | disclosed |
| CN-1580502-A | Valve train for internal combustion engine | NISSAN MOTOR (JP) | 2005-02-16 | — | — | CN | disclosed |
| CN-1573064-A | Engine piston-pin sliding structure | NISSAN MOTOR (JP) | 2005-02-02 | — | — | CN | disclosed |
| CN-1573177-A | Piston for internal combustion engine | NISSAN MOTOR (JP) | 2005-02-02 | — | — | CN | disclosed |
| CN-1573143-A | Rolling element | NISSAN MOTOR (JP) | 2005-02-02 | — | — | CN | disclosed |
| CN-1400295-A | Lubricant oil composite | NIPPON OIL CORP (JP) | 2003-03-05 | — | — | CN | disclosed |
| CN-1099454-C | Refrigerator oil composition and refrigerator fluid composition | NIPPON OIL MITSUBISHI K K (JP) | 2003-01-22 | — | — | CN | disclosed |
| CN-1376192-A | Fuel oil additive and fuel oil composition | NIPPON MITSUBISHI CO LTD (JP) | 2002-10-23 | — | — | CN | disclosed |
| CN-1306918-A | Engine oil composition for motorcycle four-stroke engine | NIPPON OIL MITSUBISHI CORP (JP) | 2001-08-08 | — | — | CN | disclosed |
| CN-1260824-A | Refrigerator oil composition and refrigerator fluid composition | NIPPON OIL MITSUBISHI K K (JP) | 2000-07-19 | — | — | CN | disclosed |
| CN-1172847-A | Fuel additive | NIPPON OIL CO LTD (JP) | 1998-02-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172556-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | PDXK, DHPS, NQO1 | NOS3 851/4885NOS2 522/4885 |
| US-20140378688-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | PDXK, DHPS, NQO1 | NOS3 851/4885NOS2 522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.