Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2814977 | 0.86 | NPC1 (0.45) | NPC1RAB9AKDM4EMAPTPOLB | |
| SCHEMBL13260938 | 0.85 | NR1I2 (0.33) | NPC1RAB9AKDM4EMAPTATM | |
| SCHEMBL9408759 | 0.84 | NPC1 (0.40) | NPC1RAB9AKDM4EMAPTATM | |
| SCHEMBL29814540 | 0.84 | NPC1 (0.45) | NPC1RAB9AKDM4EMAPTATM | |
| SCHEMBL5809113 | 0.84 | NPC1 (0.45) | NPC1RAB9AKDM4EMAPTATM | |
| SCHEMBL29349567 | 0.83 | NPC1 (0.41) | NPC1RAB9AKDM4EMAPTATM | |
| SCHEMBL29241 | 0.83 | NPC1 (0.41) | NPC1RAB9AKDM4EMAPTATM | |
| SCHEMBL20591060 | 0.81 | NPC1 (0.40) | NPC1RAB9AKDM4EMAPTATM | |
| SCHEMBL1263224 | 0.81 | ALDH1A1 (0.40) | NPC1RAB9AKDM4EMAPTATM | |
| SCHEMBL20592414 | 0.81 | NPC1 (0.39) | NPC1RAB9AKDM4EMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012097853-A1 | LIQUID CRYSTALLINE MEDIA, COMPONENTS FOR HIGH FREQUENCY TECHNOLOGY AND MESOGENIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2012-07-26 | — | — | WO | disclosed |
| US-20120119141-A1 | LIQUID CRYSTAL MEDIUM AND HIGH-FREQUENCY COMPONENTS CONTAINING THE SAME | MERCK PATENT GMBH (DE) | 2012-05-17 | — | — | US | disclosed |
| WO-2011009524-A1 | LIQUID CRYSTAL MEDIUM AND HIGH-FREQUENCY COMPONENTS CONTAINING THE SAME | MERCK PATENT GMBH (DE) | 2011-01-27 | — | — | WO | disclosed |
| EP-2100944-A1 | Liquid crystal medium and liquid crystal display | MERCK PATENT GmbH (DE) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008138456-A1 | MODULATION ELEMENTS FOR ELECTROMAGNETIC RADIATION, MODULATION DEVICE AND MODULATION MEDIUM | MERCK PATENT GMBH (DE) | 2008-11-20 | — | — | WO | disclosed |