Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19676845 | 0.81 | ADRA1D (0.42) | KMT2AHPGDTSHRMEN1ALDH1A1 | |
| SCHEMBL2228815 | 0.80 | KMT2A (0.59) | KMT2AHPGDTSHRMEN1TDP1 | |
| SCHEMBL19020742 | 0.80 | MEN1 (0.39) | KMT2AHPGDTSHRMEN1ALDH1A1 | |
| SCHEMBL20777519 | 0.80 | HPGD (0.43) | KMT2AHPGDTSHRMEN1ALDH1A1 | |
| SCHEMBL24114275 | 0.78 | KMT2A (0.43) | KMT2AHPGDMEN1ALDH1A1LMNA | |
| SCHEMBL2060980 | 0.78 | KDM4E (0.47) | KMT2AHPGDTSHRTSPOMEN1 | |
| SCHEMBL22317081 | 0.78 | KMT2A (0.40) | KMT2AHPGDTSHRMEN1ALDH1A1 | |
| SCHEMBL12287113 | 0.78 | TP53 (0.50) | KMT2AHPGDTSHRMEN1ALDH1A1 | |
| SCHEMBL11225239 | 0.78 | KMT2A (0.40) | KMT2AHPGDTSHRTSPOMEN1 | |
| SCHEMBL22844028 | 0.77 | P2RX7 (0.41) | KMT2AHPGDTSHRMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122938-A1 | Alkoxy Compounds for Disease Treatment | ACUCELA INC. (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122938-A1 | Alkoxy Compounds for Disease Treatment | ALDH1A2, CLN6, AGER | KMT2A 3103/4885HPGD 99/4885TSHR 2964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.