SCHEMBL4572164

SCHEMBL4572164

COC(=O)CCOc1ccccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BCAT1 P54687 5/20 0.38
BCAT2 O15382 3/20 0.38
LMNA P02545 3/20 0.35
MAPT P10636 2/20 0.35
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35
TSHR P16473 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
BRD4 O60885 3/20 0.34
HTT P42858 1/20 0.34
MET P08581 2/20 0.34
ALDH1A1 P00352 1/20 0.33
DHODH Q02127 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3850293 0.92 BCAT1 (0.39) BCAT1BCAT2LMNAPOLBTSHR
SCHEMBL4572166 0.90 UGCG (0.36) BCAT1BCAT2METDHODH
SCHEMBL27044947 0.86 BCAT1 (0.39) BCAT1BCAT2LMNAPOLBMEN1
SCHEMBL3245244 0.86 BCAT1 (0.39) BCAT1BCAT2LMNAPOLBTSHR
SCHEMBL29452779 0.86 BCAT1 (0.39) BCAT1BCAT2LMNAPOLBTSHR
SCHEMBL25291362 0.86 PPOX (0.37) BCAT1BCAT2LMNAMAPTMEN1
SCHEMBL13843249 0.85 PPOX (0.46) BCAT1BCAT2LMNAMAPTKDM4E
SCHEMBL13842952 0.85 ALDH1A1 (0.43) BCAT1BCAT2LMNAKDM4ETSHR
SCHEMBL27044937 0.84 BCAT1 (0.35) BCAT1BCAT2LMNAMAPTKDM4E
SCHEMBL30792811 0.84 BCAT1 (0.35) BCAT1BCAT2LMNAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293979-B2 Weed controller metabolism proteins, genes, thereof and use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-23 US disclosed
EP-2453018-A1 A herbicide metabolizing protein, a gene thereof and use thereof Sumitomo Chemical Company, Limited (JP) 2012-05-16 EP disclosed
US-20100313300-A1 WEED CONTROLLER METABOLISM PROTEINS, GENES, THEREOF AND USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED 2010-12-09 US disclosed
US-7745699-B2 Weed controller metabolism proteins, genes thereof and use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100313300-A1 WEED CONTROLLER METABOLISM PROTEINS, GENES, THEREOF AND USE OF THE SAME HADHB, WEE1, AS3MT BCAT1 166/4885BCAT2 337/4885LMNA 4368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.