SCHEMBL3245244

SCHEMBL3245244

Cn1c(C(F)(F)F)cc(=O)n(-c2cc(Oc3ccccc3OCC(=O)O)c(Cl)cc2F)c1=O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BCAT1 P54687 5/20 0.39
BCAT2 O15382 3/20 0.39
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
KMT2A Q03164 1/20 0.38
PTGDR2 Q9Y5Y4 6/20 0.36
CYP2C19 P33261 1/20 0.35
POLB P06746 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GLA P06280 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PKM P14618 1/20 0.35
RORC P51449 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29452779 1.00 BCAT1 (0.39) BCAT1BCAT2MEN1LMNAKMT2A
SCHEMBL31143246 0.94 MEN1 (0.38) BCAT1BCAT2MEN1LMNAKMT2A
SCHEMBL27047534 0.93 LMNA (0.41) BCAT1BCAT2MEN1LMNAKMT2A
SCHEMBL27044947 0.93 BCAT1 (0.39) BCAT1BCAT2MEN1LMNAKMT2A
SCHEMBL6246196 0.92 BCAT1 (0.39) BCAT1BCAT2PTGDR2POLBSMN1; SMN2
SCHEMBL3850293 0.91 BCAT1 (0.39) BCAT1BCAT2MEN1LMNAKMT2A
SCHEMBL10577900 0.91 PKM (0.40) MEN1LMNAKMT2APTGDR2CYP2C19
SCHEMBL27047504 0.91 BCAT1 (0.37) BCAT1BCAT2MEN1LMNAKMT2A
SCHEMBL13843249 0.90 PPOX (0.46) BCAT1BCAT2MEN1LMNAKMT2A
SCHEMBL27047553 0.90 PTGDR2 (0.37) MEN1LMNAKMT2APTGDR2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240229063-A1 TRANSGENIC CORN EVENT ZM_CSM63715 AND METHODS FOR DETECTION AND USES THEREOF MONSANTO TECHNOLOGY LLC (US) 2024-07-11 US claimed
EP-4200282-B1 SUBSTITUTED N-PHENYLURACILS AS WELL AS THEIR SALTS AND THEIR USE AS HERBICIDES. BAYER AG (DE) 2024-09-11 EP disclosed
US-20240229063-A1 TRANSGENIC CORN EVENT ZM_CSM63715 AND METHODS FOR DETECTION AND USES THEREOF MONSANTO TECHNOLOGY LLC (US) 2024-07-11 US disclosed
US-20240025862-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-01-25 US disclosed
US-20240025862-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-01-25 US disclosed
US-11766044-B2 Method for controlling PPO resistant weeds BASF SE (DE) 2023-09-26 US disclosed
EP-4200282-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2023-06-28 EP disclosed
CN-115996638-A Substituted N-phenyluracils and salts thereof and their use as herbicidal agents 拜耳股份有限公司 2023-04-21 CN disclosed
WO-2022043205-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2022-03-03 WO disclosed
US-11234438-B2 Protoporphyrinogen oxidase inhibitor mixtures VALENT U.S.A., LLC (US) 2022-02-01 US disclosed
EP-1106607-B1 Uracil compounds and their use SUMITOMO CHEMICAL CO (JP) 2005-07-27 EP disclosed
US-20040152597-A1 Plant growth regulators for cotton hervest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-08-05 US disclosed
US-20040138063-A1 Using an acylurea compound containing pyrimidine ring SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-07-15 US disclosed
EP-1397958-A1 STEAM/LEAF DESSICANT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-03-17 EP disclosed
US-6667413-B2 Aniline derivatives; herbicides; nonphytotoxic SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-23 US disclosed
US-20030130124-A1 Herbicides SUMITOMO CHEMICAL COMPANY, LIMITED 2003-07-10 US disclosed
WO-2002098227-A1 PLANT GROWTH REGULATORS FOR COTTON HERVEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-12-12 WO disclosed
US-6451740-B2 HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-17 US disclosed
US-20020013466-A1 Uracil compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-31 US disclosed
EP-1106607-A2 Uracil compounds and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040152597-A1 Plant growth regulators for cotton hervest GHDC, CBR3, CBR1 BCAT1 40/4885BCAT2 428/4885MEN1 3846/4885
US-20030130124-A1 Herbicides CBR3, CBR1, MT-CO1 BCAT1 492/4885BCAT2 650/4885MEN1 3863/4885
US-20020013466-A1 Uracil compounds and use thereof UNG, MRM1, OGG1 BCAT1 450/4885BCAT2 648/4885MEN1 2823/4885
US-20040138063-A1 Using an acylurea compound containing pyrimidine ring CPS1, ACACA, ODC1 BCAT1 349/4885BCAT2 1020/4885MEN1 4250/4885
US-20240025862-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES PFAS, DDT, NOTUM BCAT1 352/4885BCAT2 411/4885MEN1 4557/4885
US-11766044-B2 Method for controlling PPO resistant weeds PPOX, PNPO, NOTUM BCAT1 1472/4885BCAT2 1540/4885MEN1 4613/4885
US-11234438-B2 Protoporphyrinogen oxidase inhibitor mixtures PPOX, ACOX1, CYP51A1 BCAT1 774/4885BCAT2 709/4885MEN1 3671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.