SCHEMBL457218

SCHEMBL457218

N[C@@H](CS)C(=O)OC(=O)[C@@H](N)CSSC[C@H](N)C(=O)OC(=O)[C@@H](N)CS

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.43
SLC7A11 Q9UPY5 1/20 0.43
ENPEP Q07075 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20657045 0.87 PTGS1 (0.55) PTGS1SLC7A11ENPEP
SCHEMBL1964879 0.87 PTGS1 (0.55) PTGS1SLC7A11ENPEP
SCHEMBL8936197 0.86 ANPEP (0.41) PTGS1SLC7A11ENPEP
Hydrochloric Acid SCHEMBL11053790 0.84 PTGS1 (0.52) PTGS1SLC7A11ENPEP
Hydrochloric Acid SCHEMBL11053789 0.84 PTGS1 (0.52) PTGS1SLC7A11ENPEP
SCHEMBL1373431 0.83 PTGS1 (0.46) PTGS1SLC7A11ENPEP
SCHEMBL14775440 0.81 PTGS1 (0.38) PTGS1SLC7A11
SCHEMBL14645189 0.78 ALOX15 (0.32)
SCHEMBL2485960 0.78 PTGS1 (0.46) PTGS1SLC7A11ENPEP
SCHEMBL11125227 0.78 PTGS1 (0.50) PTGS1SLC7A11ENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12022829-B2 Water-dispersible fine particle TOYOBO CO., LTD. (JP) 2024-07-02 US disclosed
WO-2023083361-A1 NEW METHOD FOR IMPROVING QUALITY OF PLATELETS 上海循曜生物科技有限公司 2023-05-19 WO disclosed
WO-2023069598-A1 CHRONIC WOUND HEALING BIOMARKER DIAGNOSTICS THE TRUSTEES OF INDIANA UNIVERSITY (US) 2023-04-27 WO disclosed
US-20220030861-A1 WATER-DISPERSIBLE FINE PARTICLE TOYOBO CO., LTD. (JP) 2022-02-03 US disclosed
EP-3858136-A1 WATER-DISPERSIBILE FINE PARTICLE TOYOBO CO., LTD. (JP) 2021-08-04 EP disclosed
EP-3837281-A1 PROTEIN FRAGMENTATION CONTROL STRATEGY BY RE-OXIDATION IN DOWNSTREAM CHROMATOGRAPHY Bristol-Myers Squibb Company (US) 2021-06-23 EP disclosed
WO-2020241562-A1 NANOPARTICLES AND METHOD FOR PRODUCING SAME ユーハ味覚糖株式会社 2020-12-03 WO disclosed
WO-2020066912-A1 WATER DISPERSIBILE FINE PARTICLE 東洋紡株式会社 2020-04-02 WO disclosed
WO-2020037016-A1 PROTEIN FRAGMENTATION CONTROL STRATEGY BY RE-OXIDATION IN DOWNSTREAM CHROMATOGRAPHY BRISTOL-MYERS SQUIBB COMPANY (US) 2020-02-20 WO disclosed
CN-109932503-B Simulation experiment and noninvasive blood glucose detection method based on body heat production-heat dissipation model 江苏精策医疗科技有限公司 2020-02-18 CN disclosed
US-7022672-B2 Adding to the protein an aqueous solution of a charged polymer to reduce intermolecular or intramolecular interactions between positively and negatively charged domains CHIRON CORPORATION (US) 2006-04-04 US disclosed
EP-1052963-A4 COMPOSITIONS AND METHODS OF TREATING KERATIN-RELATED DISORDERS AND CONDITIONS BUCK CAROL J (US) 2003-08-06 EP disclosed
US-20020137884-A1 Formulation, solubilization, purification, and refolding of tissue factor pathway inhibitor CHIRON CORPORATION 2002-09-26 US disclosed
US-6348451-B1 WOUND HEALING AGENTS FOR ANIMALS PRO-NEURON, INC. 2002-02-19 US disclosed
EP-1052963-A1 COMPOSITIONS AND METHODS OF TREATING KERATIN-RELATED DISORDERS AND CONDITIONS Buck, Carol J. (US) 2000-11-22 EP disclosed
US-6117364-A COMPRISING CINNAMALDEHYDE AND SPECIFIED ORGANOSULFUR COMPOUND(S); FREE OF ALKYLPHENOL ETHOXY COMPOUNDS; DOES NOT HAVE OIL FIELD ALDEHYDE/POLYACRYLAMIDE CROSSLINKING INCOMPATIBILITY; FOR ACID STIMULATION OF WELLS NALCO/EXXON ENERGY CHEMICALS, L.P. (US) 2000-09-12 US disclosed
WO-1999040888-A1 COMPOSITIONS AND METHODS OF TREATING KERATIN-RELATED DISORDERS AND CONDITIONS BUCK CAROL J (US) 1999-08-19 WO disclosed
EP-0608217-A1 SOLUBLE AND STABLE SOURCES OF TYROSINE, CYSTEINE AND GLUTAMINE FOR TOTAL PARENTERAL NUTRITION RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1994-08-03 EP disclosed
EP-0608217-A4 SOLUBLE AND STABLE SOURCES OF TYROSINE, CYSTEINE AND GLUTAMINE FOR TOTAL PARENTERAL NUTRITION. RES CORP TECHNOLOGIES INC (US) 1993-12-06 EP disclosed
WO-1991016067-A1 SOLUBLE AND STABLE SOURCES OF TYROSINE, CYSTEINE AND GLUTAMINE FOR TOTAL PARENTERAL NUTRITION RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1991-10-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12022829-B2 Water-dispersible fine particle ABCG2, FIBP, MMP1 PTGS1 1898/4885SLC7A11 591/4885ENPEP 3366/4885
US-20220030861-A1 WATER-DISPERSIBLE FINE PARTICLE ABCG2, FIBP, MMP1 PTGS1 1898/4885SLC7A11 591/4885ENPEP 3366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.