Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756208 | 0.81 | KIF11 (0.33) | — | |
| SCHEMBL8933766 | 0.81 | — | — | |
| SCHEMBL2400319 | 0.80 | ALDH1A1 (0.38) | NOS1NOS2NOS3 | |
| SCHEMBL457218 | 0.78 | PTGS1 (0.43) | — | |
| SCHEMBL111172 | 0.74 | KIF11 (0.43) | NOS1NOS2NOS3 | |
| SCHEMBL525544 | 0.74 | PTGS1 (0.48) | ALOX15 | |
| SCHEMBL12438525 | 0.74 | KIF11 (0.43) | NOS1NOS2NOS3 | |
| SCHEMBL111173 | 0.74 | KIF11 (0.43) | NOS1NOS2NOS3 | |
| SCHEMBL2157572 | 0.74 | PTGS1 (0.32) | — | |
| SCHEMBL998406 | 0.74 | ALOX15 (0.44) | ALOX15NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9549964-B2 | Diagnosis, prognosis, and treatment of kidney disease | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2017-01-24 | — | — | US | disclosed |
| US-20140228296-A1 | DIAGNOSIS, PROGNOSIS, AND TREATMENT OF KIDNEY DISEASE | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2014-08-14 | — | — | US | disclosed |
| WO-2013010085-A2 | DIAGNOSIS, PROGNOSIS, AND TREATMENT OF KIDNEY DISEASE | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2013-01-17 | — | — | WO | disclosed |