SCHEMBL457259

SCHEMBL457259

Cc1ccc(OCC(N)O)cc1OCC(N)O

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
ALOX15 P16050 1/20 0.44
ACHE P22303 3/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP1A2 P05177 1/20 0.40
SCN4A P35499 2/20 0.39
ADRB2 P07550 1/20 0.39
TSHR P16473 1/20 0.37
GAA P10253 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 1/20 0.37
HTT P42858 1/20 0.37
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12446680 0.73 CYP1A2 (0.61) ALOX15ACHEKDM4ECYP1A2TSHR
SCHEMBL5426303 0.72 MAPT (0.53) KMT2ASMN1; SMN2KDM4ETSHRGAA
SCHEMBL453846 0.72 AGXT (0.48) KMT2ASMN1; SMN2ALOX15KDM4ECYP1A2
SCHEMBL28676168 0.71 KMT2A (0.50) KMT2ASMN1; SMN2TDP1MEN1HTT
SCHEMBL13651 0.70 ALOX15 (0.56) KMT2ASMN1; SMN2ALOX15ACHEKDM4E
SCHEMBL20804976 0.70 GAA (0.44) KDM4ECYP1A2GAATDP1MAPT
SCHEMBL7692656 0.70 NQO1 (0.54) KMT2AALOX15KDM4ETSHRTDP1
SCHEMBL25154981 0.69 ADRB2 (0.55) KMT2ASMN1; SMN2ALOX15KDM4ECYP1A2
SCHEMBL22275099 0.69 ADRB2 (0.55) KMT2ASMN1; SMN2ALOX15KDM4ECYP1A2
SCHEMBL11459339 0.69 LMNA (0.55) KMT2ASMN1; SMN2TDP1MEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007026313-A2 4-AMINOPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2007-03-08 WO claimed
WO-2013131575-A1 FOAMABLE COLORING COMPOSITIONS COMPRISING A THERMO-SENSITIVE POLYMER ALFAPARF GROUP S.P.A. (IT) 2013-09-12 WO disclosed
EP-2613760-A2 COMPOSITIONS FOR DYEING KERATIN FIBERS Segetis, Inc. (US) 2013-07-17 EP disclosed
WO-2012033813-A2 COMPOSITIONS FOR DYEING KERATIN FIBERS SEGETIS, INC. (US) 2012-03-15 WO disclosed
EP-2211657-A2 AIR OXIDATION HAIR DYE APPLICATION SYSTEM AND METHOD FOR COLORING HAIR USING THE SAME Combe International Ltd. (US) 2010-08-04 EP disclosed
WO-2009058700-A2 AIR OXIDATION HAIR DYE APPLICATION SYSTEM AND METHOD FOR COLORING HAIR USING THE SAME COMBE INTERNATIONAL LTD. (US) 2009-05-07 WO disclosed
WO-2008102310-A1 DYES FOR KERATINIC FIBERS COMPRISING A SPECIAL ANIONIC THICKENER THE PROCTER & GAMBLE COMPANY (US) 2008-08-28 WO disclosed
EP-1926469-A1 AGENT TO COLOR KERATIN FIBERS CONTAINING 2-AMINO-5-METHYLPHENOL AND M-AMINOPHENOLES The Procter and Gamble Company (US) 2008-06-04 EP disclosed
EP-1888023-A1 COLORANTS FOR KERATIN FIBERS Wella Aktiengesellschaft (DE) 2008-02-20 EP disclosed
EP-1855641-A1 DYE CARRIER MASS Wella Aktiengesellschaft (DE) 2007-11-21 EP disclosed
WO-2007086031-A1 COLORANTS FOR KERATIN FIBERS THE PROCTER & GAMBLE COMPANY (US) 2007-08-02 WO disclosed
WO-2007034410-A1 AGENT TO COLOR KERATIN FIBERS CONTAINING 2-AMINO-5-METHYLPHENOL AND M-AMINOPHENOLES THE PROCTER & GAMBLE COMPANY (US) 2007-03-29 WO disclosed
WO-2007026313-A2 4-AMINOPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2007-03-08 WO disclosed
WO-2007010463-A2 2-AMINO-5-AMINOMETHYL-PHENOL DERIVATIVES AND AGENT FOR COLORING KERATIN FIBERS COMPRISING THESE DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 2007-01-25 WO disclosed
WO-2006130373-A1 COLORANTS FOR KERATIN FIBERS THE PROCTER & GAMBLE COMPANY (US) 2006-12-07 WO disclosed
WO-2006099163-A1 COLOURANTS FOR KERATIN FIBRES COMPRISING CERTAIN CATIONIC CELLULOSE ETHER DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 2006-09-21 WO disclosed
WO-2006088973-A1 DYE CARRIER MASS THE PROCTER & GAMBLE COMPANY (US) 2006-08-24 WO disclosed
WO-2006081245-A1 AGENTS FOR COLORING KERATIN FIBERS THE PROCTER & GAMBLE COMPANY (US) 2006-08-03 WO disclosed
WO-2006060564-A2 PYRAZOLE AZOMETHINES AND COLORANTS CONTAINING THESE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2006-06-08 WO disclosed
WO-2004047780-A1 METHOD AND KIT FOR THE GRADUAL PERMANENT COLORING OF HAIR UNILEVER PLC (GB) 2004-06-10 WO disclosed