Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.32 |
| ▸ | KCNQ3 | O43525 | 4/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17425405 | 0.90 | JAK2 (0.32) | JAK2JAK3ACACB | |
| SCHEMBL139126 | 0.78 | TTK (0.41) | LNPEPFFAR4KCNQ3KCNQ2LOX | |
| SCHEMBL463124 | 0.75 | TTK (0.35) | LOXLOXL2 | |
| SCHEMBL105318 | 0.73 | TTK (0.37) | — | |
| SCHEMBL12986075 | 0.68 | L3MBTL1 (0.42) | HCRTR2 | |
| SCHEMBL140937 | 0.67 | LNPEP (0.34) | LNPEPACACB | |
| SCHEMBL455869 | 0.65 | TYK2 (0.41) | — | |
| SCHEMBL140752 | 0.65 | TTK (0.36) | — | |
| SCHEMBL141128 | 0.64 | ACACB (0.31) | LNPEPACACB | |
| SCHEMBL138064 | 0.64 | OPRM1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614063-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Intellectual Property GmbH (DE) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |