Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533101 | 0.71 | KMT2A (0.40) | HPGDHTTNPC1ALDH1A1PPARG | |
| SCHEMBL4573032 | 0.70 | CA2 (0.46) | — | |
| SCHEMBL28808246 | 0.70 | ALDH1A1 (0.36) | HPGDHTTNPC1ALDH1A1PPARG | |
| SCHEMBL7288669 | 0.64 | HTT (0.41) | HPGDHTTNPC1ALDH1A1PPARG | |
| SCHEMBL7296162 | 0.63 | MAPK1 (0.35) | HPGDHTTNPC1ALDH1A1PPARG | |
| SCHEMBL8791735 | 0.59 | — | — | |
| SCHEMBL16138608 | 0.58 | HPGD (0.46) | HPGDHTTNPC1ALDH1A1PPARG | |
| SCHEMBL10539247 | 0.57 | KMT2A (0.38) | L3MBTL1 | |
| SCHEMBL566998 | 0.56 | MAPK1 (0.43) | HPGDHTTNPC1ALDH1A1PPARG | |
| SCHEMBL10652126 | 0.55 | KMT2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075148-A2 | TRICYCLIC INHIBITORS OF CARBONIC ANHYDRASE | PFIZER PRODUCTS INC. (US) | 2008-06-26 | — | — | WO | disclosed |