Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11569730 | 0.81 | ALDH1A1 (0.37) | KMT2AALDH1A1HTTNPC1PPARG | |
| SCHEMBL11533430 | 0.81 | HPGD (0.40) | ALDH1A1HTTNPC1PPARGRAB9A | |
| SCHEMBL4573400 | 0.76 | ALDH1A1 (0.32) | KMT2AALDH1A1HTTNPC1PPARG | |
| SCHEMBL6287208 | 0.76 | KMT2A (0.44) | KMT2AALDH1A1HTTKDM4EHPGD | |
| SCHEMBL5141716 | 0.75 | ALDH1A1 (0.40) | KMT2AALDH1A1HTTPOLBKDM4E | |
| SCHEMBL11534203 | 0.74 | MEN1 (0.45) | KMT2AALDH1A1HTTNPC1RAB9A | |
| SCHEMBL3139450 | 0.73 | KMT2A (0.43) | KMT2AALDH1A1HTTRAB9AKDM4E | |
| SCHEMBL4574399 | 0.72 | HPGD (0.34) | ALDH1A1HTTNPC1PPARGRAB9A | |
| SCHEMBL11535382 | 0.72 | POLB (0.44) | KMT2AALDH1A1HTTPOLBKDM4E | |
| SCHEMBL11664943 | 0.71 | NPC1 (0.31) | ALDH1A1HTTNPC1PPARGRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134896-A | 5,6-Dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides, and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1979-01-16 | — | — | US | claimed |
| US-4134896-A | 5,6-Dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides, and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1979-01-16 | — | — | US | disclosed |
| US-4134900-A | 5,6-Dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides, and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1979-01-16 | — | — | US | disclosed |
| US-4098794-A | N-Thiazolyl-5,6-dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides | WARNER-LAMBERT COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4097441-A | 5,6-Dihydro-4-oxo-4H-thieno 2,3-b!thiopyran-5-carboxamides | WARNER-LAMBERT COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
| US-4092325-A | 5,6-Dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides, and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1978-05-30 | — | — | US | disclosed |