Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5127231 | 0.80 | CTSS (0.53) | CTSS | |
| SCHEMBL5127228 | 0.80 | CTSS (0.53) | CTSS | |
| SCHEMBL5131262 | 0.77 | CTSS (0.55) | CTSS | |
| SCHEMBL5131266 | 0.77 | CTSS (0.55) | CTSS | |
| SCHEMBL2975986 | 0.73 | CTSS (0.68) | CTSSHTR7 | |
| SCHEMBL4918871 | 0.71 | CTSS (0.72) | CTSSHTR7 | |
| SCHEMBL2972618 | 0.70 | CTSS (0.67) | CTSSHTR7 | |
| SCHEMBL2981470 | 0.70 | CTSS (0.69) | CTSSHTR7 | |
| SCHEMBL2980448 | 0.70 | CTSS (0.69) | CTSSHTR7 | |
| SCHEMBL2974998 | 0.68 | CTSS (0.71) | CTSSHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200454-A1 | CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S | SUNESIS PHARMACEUTICALS, INC. | 2008-08-21 | — | — | US | disclosed |
| WO-2008100618-A2 | CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S | SUNESIS PHARMACEUTICALS, INC. (US) | 2008-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200454-A1 | CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S | CTSS, CTSK, CTSZ | CTSS 1/4885HTR7 2207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.