Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 9/20 | 0.72 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2972618 | 0.86 | CTSS (0.67) | CTSSHTR7HTR1AHTR2A | |
| SCHEMBL2974998 | 0.82 | CTSS (0.71) | CTSSHTR7HTR1AHTR2A | |
| SCHEMBL2972650 | 0.78 | CTSS (0.81) | CTSS | |
| SCHEMBL2981470 | 0.77 | CTSS (0.69) | CTSSHTR7 | |
| SCHEMBL2975986 | 0.75 | CTSS (0.68) | CTSSHTR7HTR1A | |
| SCHEMBL2983711 | 0.74 | CTSS (0.81) | CTSS | |
| SCHEMBL2983694 | 0.74 | CTSS (0.83) | CTSS | |
| SCHEMBL2980448 | 0.73 | CTSS (0.69) | CTSSHTR7HTR1A | |
| SCHEMBL2984763 | 0.73 | CTSS (0.75) | CTSS | |
| SCHEMBL2076687 | 0.72 | HTR7 (0.78) | HTR7HTR1AHTR2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300255-A1 | Substituted pyrazoles | BEAVERS MARY PAT | 2008-12-04 | — | — | US | disclosed |
| US-20080293732-A1 | Substituted pyrazoles | BEAVERS MARY PAT | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293732-A1 | Substituted pyrazoles | CTSS, CTSZ, CTSB | CTSS 1/4885HTR7 3675/4885HTR1A 4383/4885 |
| US-20080300255-A1 | Substituted pyrazoles | CTSS, CTSZ, CTSB | CTSS 1/4885HTR7 3675/4885HTR1A 4383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.