Methacrylic Acid

Methacrylic Acid

SCHEMBL457408

C=C(C)C(=O)O.CCC(C)(C)C

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.44
TDP1 Q9NUW8 3/20 0.44
TET2 Q6N021 1/20 0.39
ALDH1A1 P00352 3/20 0.33
FFAR3 O14843 2/20 0.33
THRB P10828 1/20 0.32
HMGCR P04035 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
TGFBR1 P36897 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL31107008 1.00 TSHR (0.44) TSHRTDP1TET2ALDH1A1FFAR3
Methacrylic Acid SCHEMBL5174958 1.00 TSHR (0.44) TSHRTDP1TET2ALDH1A1FFAR3
Methacrylic Acid SCHEMBL8579416 1.00 TSHR (0.44) TSHRTDP1TET2ALDH1A1FFAR3
Methacrylic Acid SCHEMBL241531 1.00 TSHR (0.44) TSHRTDP1TET2ALDH1A1FFAR3
Methacrylic Acid SCHEMBL27617070 0.91 TSHR (0.36) TSHRTDP1TET2TGFBR1
Methacrylic Acid SCHEMBL28304977 0.86 TET2 (0.43) TSHRTDP1TET2ALDH1A1FFAR3
Methacrylic Acid SCHEMBL27402548 0.86 TET2 (0.43) TSHRTDP1TET2ALDH1A1FFAR3
Methacrylic Acid SCHEMBL2234573 0.86 TET2 (0.43) TSHRTDP1TET2ALDH1A1FFAR3
Methacrylic Acid SCHEMBL28712774 0.85 ALDH1A1 (0.60) TSHRTDP1TET2ALDH1A1THRB
Methacrylic Acid SCHEMBL4928189 0.84 TDP1 (0.39) TDP1TET2ALDH1A1FFAR3THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 768 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12017480-B2 Tire having a composition comprising an ethylene-rich elastomer, a peroxide and a specific acrylate derivative COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2024-06-25 US claimed
EP-3840962-B1 TYRE HAVING A COMPOSITION COMPRISING AN ETHYLENE-RICH ELASTOMER, A PEROXIDE AND A SPECIFIC ACRYLATE DERIVATIVE MICHELIN & CIE (FR) 2023-10-04 EP claimed
WO-2023161597-A1 EPOXY AMINE (METH)ACRYLATE HYDROXY URETHANE RESIN COMPOSITION Spider Resin Limited (GB) 2023-08-31 WO claimed
US-11732077-B2 Resin composition, adhesive member, and display device SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-22 US claimed
US-20210347205-A1 TIRE HAVING A COMPOSITION COMPRISING AN ETHYLENE-RICH ELASTOMER, A PEROXIDE AND A SPECIFIC ACRYLATE DERIVATIVE COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2021-11-11 US claimed
US-20180264165-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME MIDCAP FINANCIAL TRUST 2018-09-20 US claimed
US-9993576-B2 Cement products and methods of making and using the same PIONEER SURGICAL TECHNOLOGY, INC. (US) 2018-06-12 US claimed
EP-2192886-B1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME PIONEER SURGICAL TECH INC (US) 2017-12-20 EP claimed
US-20170333594-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME MIDCAP FINANCIAL TRUST 2017-11-23 US claimed
US-9757493-B2 Cement products and methods of making and using the same PIONEER SURGICAL TECHNOLOGY, INC. (US) 2017-09-12 US claimed
EP-0813740-A1 REDUCED SOLVENT ANTISTATIC HARD COAT Imation Corp (a Delaware Corporation) (US) 1997-12-29 EP claimed
EP-0808498-A1 OVERCOAT FOR OPTICAL RECORDING MEDIUM Imation Corp (a Delaware Corporation) (US) 1997-11-26 EP claimed
US-5609990-A CURED COMPOSITION OF RADIATION-CURABLE COMPONENT, NONIONIC PERFLUORO SURFACTANT, RADIATION-CURABLE SILICONE-CONTAINING COMPOUND IMATION CORP. (US) 1997-03-11 US claimed
US-5585201-A FREE FROM ORANGE PEEL TEXTURE AND HAZE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-17 US claimed
WO-1996024929-A1 REDUCED SOLVENT ANTISTATIC HARD COAT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-08-15 WO claimed
WO-1996024928-A1 OVERCOAT FOR OPTICAL RECORDING MEDIUM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-08-15 WO claimed
EP-0330115-B1 Curable adhesive composition SOMAR CORP (JP) 1994-05-11 EP claimed
US-5302654-A Production of polymer microparticles having water-insoluble chemicals immobilized therein NIPPON PAINT CO., LTD. (JP) 1994-04-12 US claimed
US-5250591-A Comprising an acrylated prepolymer, an unsaturated reactive diluent, polymerization initiator and a spherical and flaky inorganic filler; fixing chip resistors and capacitors to circuit boards for subsequent soldering SOMAR CORPORATION (JP) 1993-10-05 US claimed
EP-0177791-B1 RADIATION CURABLE PRIMER COATING COMPOSITIONS SUMITOMO METAL INDUSTRIES, LTD. (JP) 1990-08-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180264165-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME BHMT2, SHMT1, BHMT TSHR 4435/4885TDP1 4090/4885TET2 75/4885
US-20170333594-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME BHMT2, SHMT1, BHMT TSHR 4435/4885TDP1 4090/4885TET2 75/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.