Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.40 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4573197 | 0.89 | CTSB (0.46) | SUV39H2KDM4EFAAHCHRM4CCR1 | |
| SCHEMBL8109925 | 0.87 | SUV39H2 (0.48) | SUV39H2FAAHCCR1 | |
| SCHEMBL4573063 | 0.87 | SUV39H2 (0.48) | SUV39H2FAAHCCR1 | |
| SCHEMBL23855515 | 0.83 | ACACB (0.48) | FAAHKMT2ANPC1RAB9ACHRM2 | |
| SCHEMBL23855514 | 0.83 | ACACB (0.48) | FAAHKMT2ANPC1RAB9ACHRM2 | |
| SCHEMBL23855529 | 0.83 | ACACB (0.48) | FAAHKMT2ANPC1RAB9ACHRM2 | |
| SCHEMBL4585200 | 0.79 | CTSB (0.54) | SUV39H2FAAHCHRM4CCR1CTSB | |
| SCHEMBL4573735 | 0.78 | FAAH (0.42) | SUV39H2FAAHCHRM4CCR1KMT2A | |
| SCHEMBL4573827 | 0.78 | NPC1 (0.43) | SUV39H2FAAHCHRM4CCR1NPC1 | |
| SCHEMBL4573668 | 0.76 | SUV39H2 (0.50) | SUV39H2FAAHCHRM4CCR1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |