SCHEMBL4585200 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	CTSB	P07858	2/20	0.54

▸	CTSS	P25774	2/20	0.54

▸	CTSK	P43235	2/20	0.54

▸	FAAH	O00519	4/20	0.47

▸	CHRM4	P08173	3/20	0.46

▸	CCR1	P32246	2/20	0.46

▸	SUV39H2	Q9H5I1	3/20	0.46

▸	DPP4	P27487	3/20	0.44

▸	HIF1A	Q16665	1/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19096994	0.89	CTSB (0.46)	CTSBCTSSCTSKFAAHCHRM4
SCHEMBL19096985	0.89	CTSB (0.46)	CTSBCTSSCTSKFAAHCHRM4
SCHEMBL4573197	0.89	CTSB (0.46)	CTSBCTSSCTSKFAAHCHRM4
SCHEMBL4573183	0.88	CCR1 (0.46)	CTSBCTSSCTSKFAAHCHRM4
SCHEMBL4573207	0.88	SUV39H2 (0.45)	CTSBCTSSCTSKFAAHCHRM4
SCHEMBL4573031	0.88	FAAH (0.46)	CTSBCTSSCTSKFAAHCHRM4
SCHEMBL19096995	0.87	CTSB (0.46)	CTSBCTSSCTSKFAAHCHRM4
SCHEMBL4572941	0.85	CCR1 (0.44)	CTSBCTSSCTSKFAAHCHRM4
SCHEMBL4573145	0.84	SUV39H2 (0.56)	CTSBCTSSCTSKFAAHCCR1
SCHEMBL4573153	0.84	SUV39H2 (0.56)	CTSBCTSSCTSKFAAHCCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2009001127-A1	CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS	ASTRAZENECA AB (SE)	2008-12-31	—	—	WO	disclosed