Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2354327 | 0.84 | NPSR1 (0.40) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL4574469 | 0.83 | POLB (0.40) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL14013930 | 0.79 | ALDH1A1 (0.54) | L3MBTL1POLBALDH1A1KMT2ALMNA | |
| SCHEMBL2197273 | 0.78 | PSEN1 (0.37) | ALDH1A1KMT2AHSD11B1 | |
| SCHEMBL23630333 | 0.76 | MCOLN3 (0.50) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL3390197 | 0.74 | POLB (0.51) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL8098840 | 0.74 | MCOLN3 (0.50) | MCOLN3L3MBTL1POLBALDH1A1KMT2A | |
| SCHEMBL14013791 | 0.74 | HTT (0.51) | POLBALDH1A1KMT2ALMNANPSR1 | |
| SCHEMBL2197409 | 0.73 | HSD11B1 (0.43) | ALDH1A1HSD11B1 | |
| SCHEMBL3386468 | 0.72 | ALDH1A1 (0.36) | ALDH1A1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134035-A1 | ALPHA-UNSUBSTITUTED ARYLMETHYL PIPERAZINE PYRAZOLO[1,5-A] PYRIMIDINE AMIDE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |