Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 9/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triethylene Glycol SCHEMBL4929291 | 1.00 | FFAR2 (0.36) | FFAR2FDPSPTGESHPGDSNR3C1 | |
| SCHEMBL170782 | 0.83 | — | — | |
| SCHEMBL17097343 | 0.81 | POLB (0.38) | FFAR2FDPSPTGESHPGDSNR3C1 | |
| Hexaethylene Glycol SCHEMBL25401683 | 0.72 | NPC1 (0.35) | MEN1KMT2A | |
| SCHEMBL7342758 | 0.70 | FDPS (0.48) | FFAR2FDPSPTGESHPGDSNR3C1 | |
| SCHEMBL8819697 | 0.70 | FDPS (0.48) | FFAR2FDPSPTGESHPGDSNR3C1 | |
| SCHEMBL8392811 | 0.70 | KMT2A (0.46) | FFAR2FDPSPTGESHPGDSKMT2A | |
| Imidazole SCHEMBL30284460 | 0.69 | ALDH1A1 (0.38) | FFAR2FDPSPTGESHPGDSNR3C1 | |
| SCHEMBL10611216 | 0.68 | FDPS (0.43) | FFAR2FDPSPTGESHPGDSNR3C1 | |
| SCHEMBL16814871 | 0.68 | TUBB4A (0.46) | FFAR2FDPSHPGDSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242179-B2 | Hydrogel-based joint repair system and method | SURMODICS, INC. (US) | 2012-08-14 | — | — | US | disclosed |
| US-20080039931-A1 | Hydrophilic shape memory insertable medical articles | SURMODICS, INC. | 2008-02-14 | — | — | US | disclosed |
| US-20080021563-A1 | Hydrogel-based joint repair system and method | SURMODICS, INC. | 2008-01-24 | — | — | US | disclosed |
| WO-2008002482-A2 | HYDROGEL-BASED JOINT REPAIR SYSTEM AND METHOD | SURMODICS, INC. (US) | 2008-01-03 | — | — | WO | disclosed |