Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | GALK1 | P51570 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896700 | 0.80 | METAP2 (0.46) | ALDH1A1BACE1HPRT1LMNAMAPT | |
| SCHEMBL8928083 | 0.76 | ALDH1A1 (0.50) | ALDH1A1BACE1PTPN1CRHBPCRHR2 | |
| SCHEMBL22064851 | 0.74 | CYP2A6 (0.50) | ALDH1A1BACE1PTPN1CRHBPCRHR2 | |
| SCHEMBL309669 | 0.74 | PTPN1 (0.50) | ALDH1A1BACE1PTPN1CRHBPCRHR2 | |
| SCHEMBL96797 | 0.74 | ALDH1A1 (0.47) | ALDH1A1BACE1PTPN1CRHBPCRHR2 | |
| SCHEMBL18388982 | 0.74 | ALDH1A1 (0.47) | ALDH1A1BACE1PTPN1CRHBPCRHR2 | |
| SCHEMBL456551 | 0.74 | ALDH1A1 (0.47) | ALDH1A1BACE1PTPN1CRHBPCRHR2 | |
| SCHEMBL20663065 | 0.74 | PTGS1 (0.58) | ALDH1A1BACE1PTPN1CRHBPCRHR2 | |
| SCHEMBL22064850 | 0.74 | ALDH1A1 (0.47) | ALDH1A1BACE1PTPN1CRHBPCRHR2 | |
| SCHEMBL1638704 | 0.74 | IKBKB (0.51) | ALDH1A1BACE1PTPN1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9457347-B2 | Olefin metathesis catalysts | BERGEN TEKNOLOGIOVERFORING AS (NO) | 2016-10-04 | — | — | US | disclosed |
| EP-2613878-B1 | NOVEL OLEFIN METATHESIS CATALYSTS | BERGEN TEKNOLOGIOVERFØRING AS (NO) | 2016-07-27 | — | — | EP | disclosed |
| US-20140357478-A1 | NOVEL OLEFIN METATHESIS CATALYSTS | BERGEN TEKNOLOGIOVERFORING AS (NO) | 2014-12-04 | — | — | US | disclosed |
| US-8716488-B2 | Olefin metathesis catalysts | BERGEN TEKNOLOGIOVERFORING AS (NO) | 2014-05-06 | — | — | US | disclosed |
| EP-2613878-A1 | NOVEL OLEFIN METATHESIS CATALYSTS | Bergen Teknologioverforing AS (NO) | 2013-07-17 | — | — | EP | disclosed |
| US-20130023665-A1 | NOVEL OLEFIN METATHESIS CATALYSTS | BERGEN TEKNOLOGIOVERFORING AS (NO) | 2013-01-24 | — | — | US | disclosed |
| WO-2012032131-A1 | NOVEL OLEFIN METATHESIS CATALYSTS | BERGEN TEKNOLOGIOVERFØRING AS (NO) | 2012-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357478-A1 | NOVEL OLEFIN METATHESIS CATALYSTS | OCIAD2, OCIAD1, OXER1 | ALDH1A1 1398/4885BACE1 2891/4885PTPN1 4481/4885 |
| US-20130023665-A1 | NOVEL OLEFIN METATHESIS CATALYSTS | OCIAD2, OCIAD1, OXER1 | ALDH1A1 1398/4885BACE1 2891/4885PTPN1 4481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.