Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31152626 | 0.83 | RECQL (0.50) | CYP3A4CYP2C9RECQLAKR1C3KMT2A | |
| SCHEMBL9354507 | 0.82 | CYP3A4 (0.54) | CYP3A4CYP2C9RECQLAKR1C3AKR1C1 | |
| SCHEMBL9354466 | 0.81 | CYP3A4 (0.53) | CYP3A4CYP2C9RECQLAKR1C3ALDH1A1 | |
| SCHEMBL57683 | 0.79 | CYP3A4 (0.63) | CYP3A4CYP2C9RECQLAKR1C3AKR1C1 | |
| SCHEMBL2918640 | 0.79 | CYP3A4 (0.63) | CYP3A4CYP2C9RECQLAKR1C3AKR1C1 | |
| SCHEMBL309762 | 0.79 | CYP3A4 (0.63) | CYP3A4CYP2C9RECQLAKR1C3AKR1C1 | |
| SCHEMBL524131 | 0.76 | ALOX5 (0.59) | CYP3A4CYP2C9RECQLAKR1C3KMT2A | |
| SCHEMBL8702152 | 0.76 | ALOX5 (0.59) | CYP3A4CYP2C9RECQLAKR1C3KMT2A | |
| SCHEMBL1786246 | 0.76 | ALOX5 (0.59) | CYP3A4CYP2C9RECQLAKR1C3KMT2A | |
| SCHEMBL9504328 | 0.76 | RECQL (0.59) | CYP3A4CYP2C9RECQLAKR1C3AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008039087-A2 | INDOLINE DERIVATIVES AND USES THEREOF | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-04-03 | — | — | WO | disclosed |