SCHEMBL457581

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20659270	0.84	BRD4 (0.47)	MAPTCYP3A4CYP2D6CYP1A2MAPK1
	SCHEMBL108857	0.83	BRD4 (0.63)	MAPTCYP3A4CYP2D6CYP1A2MAPK1
	SCHEMBL14263011	0.82	MAPT (0.53)	MAPTCYP3A4CYP2D6CYP1A2MAPK1
	SCHEMBL18974115	0.79	GAA (0.52)	MAPTCYP3A4CYP2D6CYP1A2MAPK1
	SCHEMBL18043964	0.78	BRD4 (0.57)	MAPTCYP3A4CYP2D6CYP1A2MAPK1
	SCHEMBL14263026	0.78	BRD4 (0.50)	MAPTCYP3A4CYP2D6CYP1A2MAPK1
	SCHEMBL29601684	0.78	BRD4 (0.50)	MAPTCYP3A4CYP2D6CYP1A2MAPK1
	SCHEMBL4244032	0.76	BRD4 (0.55)	MAPTCYP3A4CYP2D6CYP1A2MAPK1
	SCHEMBL22480913	0.76	BRD4 (0.44)	MAPTCYP3A4CYP2D6CYP1A2MAPK1
	SCHEMBL129298	0.75	BRD4 (0.51)	MAPTCYP3A4CYP2D6CYP1A2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.