Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.65 |
| ▸ | CTSB | P07858 | 5/20 | 0.65 |
| ▸ | CTSS | P25774 | 4/20 | 0.65 |
| ▸ | CTSK | P43235 | 8/20 | 0.64 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27715045 | 1.00 | CTSL (0.65) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL5193470 | 0.92 | CTSS (0.64) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL27715313 | 0.92 | CTSS (0.64) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL5134409 | 0.92 | CTSL (0.72) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL25406813 | 0.91 | CTSK (0.77) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL20770085 | 0.91 | CTSK (0.77) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL14148467 | 0.91 | CTSK (0.77) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL8823918 | 0.91 | CTSK (0.77) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL4872585 | 0.91 | CTSK (0.77) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL2930262 | 0.91 | CTSK (0.77) | CTSLCTSBCTSSCTSKCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718611-B2 | Cyclic nonapeptide amides | AICURIS GMBH & CO. KG (DE) | 2010-05-18 | — | — | US | disclosed |
| US-7718611-B2 | Cyclic nonapeptide amides | AICURIS GMBH & CO. KG (DE) | 2010-05-18 | — | — | US | disclosed |
| US-7399778-B2 | Heterocyclic sulfonamide inhibitors of beta amyloid production containing an azole | WYETH (US) | 2008-07-15 | — | — | US | disclosed |
| US-20080070884-A1 | Antibiotics; novel class of cell wall biosynthesis inhibitors without cross-resistances to known classes of antibiotics; active analogs of lysobactin with a higher ring stability | AICURIS GMBH & CO. KG (DE) | 2008-03-20 | — | — | US | disclosed |
| US-20080070884-A1 | Antibiotics; novel class of cell wall biosynthesis inhibitors without cross-resistances to known classes of antibiotics; active analogs of lysobactin with a higher ring stability | AICURIS GMBH & CO. KG (DE) | 2008-03-20 | — | — | US | disclosed |
| US-20080070884-A1 | Antibiotics; novel class of cell wall biosynthesis inhibitors without cross-resistances to known classes of antibiotics; active analogs of lysobactin with a higher ring stability | AICURIS GMBH & CO. KG (DE) | 2008-03-20 | — | — | US | disclosed |
| EP-1809657-A1 | CYCLIC NONAPEPTIDE AMIDES | AiCuris GmbH & Co. KG (DE) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006048156-A1 | CYCLIC NONAPEPTIDE AMIDES | AICURIS GMBH & CO. KG (DE) | 2006-05-11 | — | — | WO | disclosed |
| US-20050171180-A1 | Heterocyclic sulfonamide inhibtors of beta amyloid production containing an azole | WYETH (US) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070884-A1 | Antibiotics; novel class of cell wall biosynthesis inhibitors without cross-resistances to known classes of antibiotics; active analogs of lysobactin with a higher ring stability | AAAS, PGLS, NRDC | CTSL 360/4885CTSB 313/4885CTSS 339/4885 |
| US-20050171180-A1 | Heterocyclic sulfonamide inhibtors of beta amyloid production containing an azole | IAPP, APP, CBR3 | CTSL 3387/4885CTSB 2298/4885CTSS 1679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.