SCHEMBL457595

SCHEMBL457595

COCc1c(F)c(F)c(C)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 1/20 0.35
SRC P12931 1/20 0.35
AXL P30530 1/20 0.35
PTK2 Q05397 1/20 0.35
AURKB Q96GD4 1/20 0.35
ALK Q9UM73 1/20 0.35
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
IMPDH2 P12268 1/20 0.31
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7107814 0.89 IGF1R (0.31) IGF1RSRCAXLPTK2AURKB
SCHEMBL14708745 0.86 CA12 (0.32) IGF1RSRCAXLPTK2AURKB
SCHEMBL19688655 0.80 GCGR (0.36) IGF1RSRCAXLPTK2AURKB
SCHEMBL14299921 0.79 GCGR (0.30)
SCHEMBL359266 0.77 GCGR (0.39) IGF1RSRCAXLPTK2AURKB
SCHEMBL1785291 0.77
SCHEMBL1900289 0.77 IGF1R (0.31) IGF1RSRCAXLPTK2AURKB
SCHEMBL21166950 0.77 KDM4E (0.33) HPGD
SCHEMBL27833797 0.77 HSD17B10 (0.32) HSD17B10IMPDH2
SCHEMBL117187 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240057602-A1 DIAMIDE INSECTICIDE COMPOSITIONS FMC IP TECHNOLOGY GMBH (CH) 2024-02-22 US claimed
US-20230026036-A1 DIAMIDE SUSPENSION CONCENTRATE COMPOSITIONS FMC IP TECHNOLOGY GMBH (CH) 2023-01-26 US claimed
EP-3887354-B1 META-DIAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC CORP (US) 2023-01-04 EP claimed
US-20220394974-A1 MIXTURES COMPRISING INDAZOLE PESTICIDES FMC CORPORATION 2022-12-15 US claimed
EP-4013223-A1 MATERIAL DELIVERY SYSTEMS AND METHODS FMC Corporation (US) 2022-06-22 EP claimed
EP-3996508-A1 MIXTURES COMPRISING INDAZOLE PESTICIDES FMC Corporation (US) 2022-05-18 EP claimed
US-20210400977-A1 META-DIAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC CORPORATION 2021-12-30 US claimed
EP-3887354-A1 META-DIAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC Corporation (US) 2021-10-06 EP claimed
WO-2021127126-A1 DIAMIDE SUSPENSION CONCENTRATE COMPOSITIONS FMC CORPORATION (US) 2021-06-24 WO claimed
WO-2021067678-A1 DIAMIDE INSECTICIDE COMPOSITIONS FMC CORPORATION (US) 2021-04-08 WO claimed
WO-2021030540-A1 MATERIAL DELIVERY SYSTEMS AND METHODS FMC CORPORATION (US) 2021-02-18 WO claimed
WO-2021007545-A1 MIXTURES COMPRISING INDAZOLE PESTICIDES FMC CORPORATION (US) 2021-01-14 WO claimed
WO-2020112390-A1 META-DIAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC CORPORATION (US) 2020-06-04 WO claimed
EP-0939073-B1 Ester of 2,2-dimethyl-cyclopropanecarboxylic acid and their use as pesticides SUMITOMO CHEMICAL CO (JP) 2002-12-04 EP claimed
EP-0939073-A1 Ester of 2,2-dimethyl-cyclopropanecarboxylic acid and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-01 EP claimed
US-20240215577-A1 FUNGICIDAL PYRIDONES FMC CORPORATION 2024-07-04 US disclosed
WO-2024137629-A1 AZOLE COMPOUNDS FOR CONTROLLING AND COMBATING INVERTEBRATE PESTS FMC CORPORATION (US) 2024-06-27 WO disclosed
CN-101346334-A Tetrafluorotoluene compound, method for producing same and use thereof SUMITOMO CHEMICAL CO (JP) 2009-01-14 CN disclosed
EP-2011764-A1 POTASSIUM FLUORIDE DISPERSION SOLUTION, AND PROCESS FOR PRODUCTION OF FLUORINATED ORGANIC COMPOUND USING THE SAME Sumitomo Chemical Company, Limited (JP) 2009-01-07 EP disclosed
EP-1975147-A1 TETRAFLUOROTOLUENE COMPOUND, METHOD FOR PRODUCING SAME AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2008-10-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210400977-A1 META-DIAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS DDT, RDX, ACHE IGF1R 2643/4885SRC 3440/4885AXL 3315/4885
US-20240057602-A1 DIAMIDE INSECTICIDE COMPOSITIONS DDT, PLCG2, PLD2 IGF1R 3768/4885SRC 3559/4885AXL 822/4885
US-20240215577-A1 FUNGICIDAL PYRIDONES PNPO, CYP1B1, CYP1A1 IGF1R 2099/4885SRC 4004/4885AXL 2841/4885
US-20220394974-A1 MIXTURES COMPRISING INDAZOLE PESTICIDES ACHE, DDT, BCHE IGF1R 553/4885SRC 1275/4885AXL 2359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.