Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3235309 | 0.84 | TRPM8 (0.39) | MEN1KMT2ATRPM8MAPTL3MBTL1 | |
| SCHEMBL28679035 | 0.73 | ALDH1A1 (0.37) | MEN1KMT2AMAPTL3MBTL1POLB | |
| SCHEMBL28679034 | 0.73 | ALDH1A1 (0.37) | MEN1KMT2AMAPTL3MBTL1POLB | |
| SCHEMBL4730706 | 0.72 | ALDH1A1 (0.44) | MEN1KMT2AMAPTL3MBTL1GAA | |
| SCHEMBL2052140 | 0.72 | SRD5A2 (0.33) | MEN1KMT2AMAPTHTT | |
| SCHEMBL16468178 | 0.72 | SRD5A2 (0.33) | MEN1KMT2AMAPTHTT | |
| SCHEMBL12332811 | 0.71 | MAPT (0.53) | MEN1KMT2AMAPT | |
| SCHEMBL15200245 | 0.71 | MAPT (0.53) | MEN1KMT2AMAPT | |
| SCHEMBL1286694 | 0.71 | MAPT (0.53) | MEN1KMT2AMAPT | |
| SCHEMBL15199107 | 0.70 | HSD11B1 (0.34) | MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008040451-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITIONS WITH A CONTENT OF 2-ISOPROPYL-5- METHYL-CYCLOHEXANCARBONYL-D-ALANINE ETHYL ESTER AND ONE OR MORE ANTIOXIDANTS | BEIERSDORF AG (DE) | 2008-04-10 | — | — | WO | disclosed |