Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1911777 | 0.76 | CES2 (0.42) | ALDH1A1NPSR1TSHRSMN1; SMN2 | |
| SCHEMBL12375165 | 0.74 | CES2 (0.39) | MEN1KMT2ANPSR1TSHRGAA | |
| SCHEMBL25914172 | 0.74 | CES2 (0.37) | ALDH1A1CTSKHPGDTSHRSMN1; SMN2 | |
| SCHEMBL3235309 | 0.73 | TRPM8 (0.39) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL4576002 | 0.72 | MEN1 (0.37) | MAPTL3MBTL1MEN1KMT2AGAA | |
| Bicarbonate SCHEMBL7267969 | 0.72 | HDAC8 (0.40) | — | |
| SCHEMBL13603964 | 0.72 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6899690 | 0.71 | ALDH1A1 (0.50) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL18843977 | 0.71 | CES2 (0.34) | ALDH1A1CTSKNPSR1HPGDTSHR | |
| SCHEMBL10741232 | 0.71 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1MEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008040459-A1 | COSMETIC OR DERMATOLOGICAL PREPARATIONS WITH A CONTENT OF 2-ISOPROPYL-5-METHYL-CYCLOHEXANECARBONYL-D-ALANINE ETHYL ESTER AND ONE OR MORE SKIN BLEACHING AGENTS FOR TREATING UNWANTED PIGMENTATION OF THE SKIN IN PARTICULAR POSTINFLAMMATORY HYPERPIGMENTATION | BEIERSDORF AG (DE) | 2008-04-10 | — | — | WO | disclosed |