Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4578589 | 0.82 | TSHR (0.47) | HTTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL28548807 | 0.82 | SLC6A3 (0.48) | HTTGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL11152302 | 0.82 | HTT (0.54) | HTTGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL3686832 | 0.79 | LMNA (0.53) | HTTGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL4528195 | 0.77 | FOLH1 (0.44) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4576988 | 0.77 | HTT (0.47) | HTTGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL13228930 | 0.76 | HTT (0.62) | HTTGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL69682 | 0.75 | SLC6A3 (0.57) | HTTGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL27518863 | 0.75 | PTPN22 (0.45) | ALDH1A1MAPTHSD17B10 | |
| SCHEMBL5700615 | 0.73 | SLC6A3 (0.72) | HTTGABRA1GABRG2GABRB3GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1586569-B1 | Aryl ethynyl phthalic acid derivative and method for producing the same | FUJIFILM CORP (JP) | 2012-06-06 | — | — | EP | disclosed |
| US-7339071-B2 | Aryl ethynyl phthalic acid derivative and method for producing the same | FUJIFILM CORPORATION (JP) | 2008-03-04 | — | — | US | disclosed |
| EP-1586569-A1 | Aryl ethynyl phthalic acid derivative and method for producing the same | FUJI PHOTO FILM CO., LTD. (JP) | 2005-10-19 | — | — | EP | disclosed |
| US-20050215820-A1 | Aryl ethynyl phthalic acid derivative and method for producing the same | FUJI PHOTO FILM CO., LTD. | 2005-09-29 | — | — | US | disclosed |