Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4577844 | 1.00 | ALDH1A1 (0.48) | ALDH1A1ALPIPKMPTGS1XIAP | |
| SCHEMBL31553563 | 0.82 | ALDH1A1 (0.53) | ALDH1A1ALPIPKMPTGS1XIAP | |
| SCHEMBL31360808 | 0.81 | SRR (0.49) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL9028692 | 0.81 | ALDH1A1 (0.52) | ALDH1A1ALPIPKMPTGS1XIAP | |
| SCHEMBL5617244 | 0.81 | ALDH1A1 (0.52) | ALDH1A1ALPIPKMPTGS1XIAP | |
| SCHEMBL3505882 | 0.81 | ALDH1A1 (0.52) | ALDH1A1ALPIPKMPTGS1XIAP | |
| SCHEMBL8467355 | 0.79 | ALDH1A1 (0.50) | ALDH1A1ALPIPKMPTGS1XIAP | |
| SCHEMBL1786356 | 0.79 | ALPI (0.44) | ALDH1A1ALPIPKMPTGS1XIAP | |
| SCHEMBL8921434 | 0.79 | ALDH1A1 (0.46) | ALDH1A1ALPIPKMPTGS1XIAP | |
| SCHEMBL9153847 | 0.78 | FOLH1 (0.44) | ALDH1A1PTGS1CYP1A2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954815-A2 | PRODUCTION OF GLYCOPROTEINS WITH REDUCED O-GLYCOSYLATION | Glycofi, Inc. (US) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007061631-A2 | PRODUCTION OF GLYCOPROTEINS WITH REDUCED O-GLYCOSYLATION | GLYCOFI, INC (US) | 2007-05-31 | — | — | WO | disclosed |