SCHEMBL8467355

SCHEMBL8467355

CC(=O)OC(O)Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
ALPI P09923 1/20 0.50
PKM P14618 1/20 0.50
PTGS1 P23219 1/20 0.50
XIAP P98170 1/20 0.50
SLC7A5 Q01650 1/20 0.50
CYP1A2 P05177 1/20 0.48
SRR Q9GZT4 2/20 0.46
TSHR P16473 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
CTRB1 P17538 4/20 0.45
LAP3 P28838 1/20 0.45
ALPL P05186 1/20 0.44
POLB P06746 1/20 0.44
ALPG P10696 1/20 0.44
MDM2 Q00987 1/20 0.44
PPARG P37231 1/20 0.44
PPARA Q07869 1/20 0.44
MTNR1A P48039 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11436119 0.84 CYP1A2 (0.52) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL31553563 0.84 ALDH1A1 (0.53) ALDH1A1ALPIPKMPTGS1XIAP
SCHEMBL3505882 0.82 ALDH1A1 (0.52) ALDH1A1ALPIPKMPTGS1XIAP
SCHEMBL5617244 0.82 ALDH1A1 (0.52) ALDH1A1ALPIPKMPTGS1XIAP
SCHEMBL9028692 0.82 ALDH1A1 (0.52) ALDH1A1ALPIPKMPTGS1XIAP
SCHEMBL964645 0.82 ALPI (0.44) ALDH1A1ALPIPKMPTGS1XIAP
SCHEMBL23494910 0.81 TSHR (0.47) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL9467203 0.81 TSHR (0.47) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL4577144 0.79 ALDH1A1 (0.48) ALDH1A1ALPIPKMPTGS1XIAP
SCHEMBL1486323 0.79 SRR (0.62) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5151546-A Process for the production of 4-acetoxystyrene, its polymers and hydrolysis products HOECHST CELANESE CORPORATION (US) 1992-09-29 US claimed
US-5929204-A Process for removing metals from vinylphenol-type polymers MARUZEN PETROCHEMICAL CO., LTD. (JP) 1999-07-27 US disclosed
EP-0860451-A1 Process for removing metals from vinylphenol-type polymers MARUZEN PETROCHEMICAL CO., LTD. (JP) 1998-08-26 EP disclosed
WO-1996019433-A1 PROCESS FOR PREPARING ACETOXYSTYRENE HOECHST CELANESE CORPORATION (US) 1996-06-27 WO disclosed
EP-0544324-B1 Process for removing metals from vinylphenol polymers MARUZEN PETROCHEM CO LTD (JP) 1996-01-31 EP disclosed
US-5288850-A Adsorbing on acidic, cationic exchange resin from dissolved polymer MARUZEN PETROCHEMICAL CO., LTD. (JP) 1994-02-22 US disclosed
US-5274173-A Process for the production of poly(4-acetoxystyrene) HOECHST CELANESE CORPORATION (US) 1993-12-28 US disclosed
US-5274174-A Process for the production of poly(4-hydroxystyrene) HOECHST CELANESE CORPORATION (US) 1993-12-28 US disclosed
US-5274175-A Process for the preparation of 4-acetoxyphenylmethyl carbinol HOECHST CELANESE CORPORATION (US) 1993-12-28 US disclosed
US-5245074-A Process for the production of 4-acetoxystyrene, its polymers and hydrolysis products CLARIANT AG (CH) 1993-09-14 US disclosed
EP-0544324-A1 Process for removing metals from vinylphenol polymers MARUZEN PETROCHEMICAL CO., LTD. (JP) 1993-06-02 EP disclosed
US-5151546-A Process for the production of 4-acetoxystyrene, its polymers and hydrolysis products HOECHST CELANESE CORPORATION (US) 1992-09-29 US disclosed
EP-0449603-A1 Production of 4-hydroxyphenethyl alcohol HOECHST CELANESE CORPORATION (US) 1991-10-02 EP disclosed
US-5003115-A Epoxidation of acetoxystyrene with a percarboxylic acid to produce acetoxyphenyl oxirane, hydrogenation followed by saponification HOECHST CELANESE CORPORATION (US) 1991-03-26 US disclosed
CN-1039411-A The short residence time(SRT) evaporation of right-acetoxyl phenylmethylcarbinol HOECHST CELANESE CORP (US) 1990-02-07 CN disclosed
CN-1039412-A The solvent-free hydrogenation of 4-acetoxyl methyl phenyl ketone prepares 4-acetoxystyrene and polymkeric substance and hydrolysate HOECHST CELANESE CORP (US) 1990-02-07 CN disclosed