Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.47 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GGH | Q92820 | 1/20 | 0.41 |
| ▸ | GNPAT | O15228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4577277 | 1.00 | FOLH1 (0.47) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| SCHEMBL19177132 | 1.00 | FOLH1 (0.47) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| SCHEMBL10552726 | 0.89 | FOLH1 (0.47) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| SCHEMBL10872510 | 0.89 | FOLH1 (0.47) | FOLH1NAALAD2RIMKLAKDM4EMAPT | |
| SCHEMBL19177184 | 0.87 | FOLH1 (0.40) | FOLH1NAALAD2RIMKLATHRBPLA2G2C | |
| SCHEMBL19177136 | 0.86 | FOLH1 (0.50) | FOLH1ALDH1A1 | |
| SCHEMBL12064029 | 0.86 | SMN1; SMN2 (0.45) | FOLH1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL12064041 | 0.86 | SMN1; SMN2 (0.45) | FOLH1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL12064309 | 0.86 | SMN1; SMN2 (0.45) | FOLH1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL11124586 | 0.85 | L3MBTL1 (0.56) | FOLH1NAALAD2RIMKLAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284872-A | Nitrato alkanoic acid derivatives, methods for their production, pharmaceutical compositions containing the derivatives and medicinal uses thereof | SCHWARZ PHARMA AG (DE) | 1994-02-08 | — | — | US | claimed |
| US-20240103005-A1 | N-ACRYLOYLINDOLES AND METHODS OF USE | VERSITECH LIMITED (CN) | 2024-03-28 | — | — | US | disclosed |
| CN-117126096-A | N-acryloylindoles and methods of use | 香港大学 | 2023-11-28 | — | — | CN | disclosed |
| EP-1414432-A4 | METHODS OF USE FOR NOVEL SULFUR CONTAINING ORGANIC NITRATE COMPOUNDS | NITROMED INC (US) | 2008-01-09 | — | — | EP | disclosed |
| US-20040152753-A1 | Methods of use for novel sulfur containing organic nitrate compounds | NITROMED, INC. | 2004-08-05 | — | — | US | disclosed |
| EP-1414432-A2 | METHODS OF USE FOR NOVEL SULFUR CONTAINING ORGANIC NITRATE COMPOUNDS | Nitromed, Inc. (US) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003013432-A2 | METHODS OF USE FOR NOVEL SULFUR CONTAINING ORGANIC NITRATE COMPOUNDS | NITROMED, INC. (US) | 2003-02-20 | — | — | WO | disclosed |
| US-5284872-A | Nitrato alkanoic acid derivatives, methods for their production, pharmaceutical compositions containing the derivatives and medicinal uses thereof | SCHWARZ PHARMA AG (DE) | 1994-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240103005-A1 | N-ACRYLOYLINDOLES AND METHODS OF USE | NAT1, DDIT3, ACR | FOLH1 3147/4885NAALAD2 676/4885RIMKLA 1239/4885 |
| US-20040152753-A1 | Methods of use for novel sulfur containing organic nitrate compounds | PTGS2, NOS2, PTGS1 | FOLH1 2150/4885NAALAD2 4526/4885RIMKLA 1283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.