Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.32 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2757992 | 0.76 | CA2 (0.48) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL22971344 | 0.72 | CA2 (0.43) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL7478228 | 0.72 | CA2 (0.43) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL27524175 | 0.71 | CA2 (0.39) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL2597673 | 0.70 | — | — | |
| SCHEMBL4463196 | 0.70 | KDM4C (0.42) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL1618588 | 0.69 | CA2 (0.53) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL4469009 | 0.68 | KDM4C (0.41) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL28995827 | 0.68 | CA2 (0.40) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL4469005 | 0.68 | CA2 (0.40) | CA2ALDH1A1POLBSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462451-B2 | Compositions for modifying nucleic acids | THIRD WAVE TECHNOLOGIES, INC. (US) | 2008-12-09 | — | — | US | disclosed |
| US-20050277138-A1 | Reactive functional groups | THIRD WAVE TECHNOLOGIES, INC. (US) | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277138-A1 | Reactive functional groups | RNGTT, POLRMT, NSUN2 | CA2 1611/4885ALDH1A1 2481/4885POLB 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.