SCHEMBL457744

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28067065	0.91	XDH (0.56)	XDHAPPMAPTLMNAGAA
	SCHEMBL27908158	0.80	XDH (0.56)	XDHAPPMAPTLMNAGAA
	Hydrochloric Acid SCHEMBL158931	0.78	XDH (0.55)	XDHAPPMAPTLMNAGAA
	SCHEMBL1756208	0.78	XDH (0.57)	XDHAPPMAPTLMNAGAA
	Hydrochloric Acid SCHEMBL162850	0.77	XDH (0.53)	XDHAPPMAPTLMNAGAA
	SCHEMBL14541793	0.76	XDH (0.56)	XDHAPPMAPTLMNAGAA
	SCHEMBL20379759	0.76	XDH (0.76)	XDHAPPMAPTLMNAGAA
	SCHEMBL12091997	0.76	CSNK2A1 (0.62)	APPMAPTGAACSNK2A1ALDH1A1
	Hydrochloric Acid SCHEMBL163366	0.76	XDH (0.52)	XDHAPPMAPTLMNAGAA
	Hydrochloric Acid SCHEMBL28805026	0.75	XDH (0.55)	XDHAPPMAPTLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.