Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1756208 | 0.86 | XDH (0.57) | XDHAPPMAPTLMNAALDH1A1 | |
| SCHEMBL457744 | 0.80 | XDH (0.60) | XDHAPPTSHRMAPTLMNA | |
| SCHEMBL1756309 | 0.78 | RAB9A (0.55) | XDHMAPTALDH1A1GAAKDM4E | |
| SCHEMBL2678850 | 0.77 | KDR (0.53) | CYP1A2CYP3A4CSNK2A1 | |
| SCHEMBL27915214 | 0.76 | GAA (0.63) | XDHAPPTSHRMAPTLMNA | |
| SCHEMBL5875845 | 0.75 | CRHBP (0.56) | TSHRMAPTLMNAALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL158931 | 0.75 | XDH (0.55) | XDHAPPMAPTLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL162850 | 0.74 | XDH (0.53) | XDHAPPMAPTLMNAALDH1A1 | |
| SCHEMBL20379759 | 0.73 | XDH (0.76) | XDHAPPMAPTLMNAALDH1A1 | |
| SCHEMBL14541793 | 0.73 | XDH (0.56) | XDHAPPMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947280-A | Carboxy-oxazole or thiazole compounds as DGAT-1 inhibitors useful for the treatment of obesity | PIRAMAL LIFE SCIENCES LTD | 2013-02-27 | — | — | CN | disclosed |