Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Piperidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azepane SCHEMBL714889 | 1.00 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2CXCR4CA2CHKA | |
| Piperidine SCHEMBL720107 | 1.00 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2CXCR4CA2CHKA | |
| Azepane SCHEMBL20740115 | 0.97 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2CXCR4CA2CHKA | |
| Azepane SCHEMBL940042 | 0.97 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2CXCR4CA2CHKA | |
| Pyrrolidine SCHEMBL712847 | 0.96 | — | — | |
| Piperidine SCHEMBL5875101 | 0.90 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2CXCR4CA2CHKA | |
| Piperidine SCHEMBL2483462 | 0.90 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2CXCR4CA2CHKA | |
| Azetidine SCHEMBL7551428 | 0.89 | — | — | |
| Piperidine SCHEMBL10332243 | 0.87 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2CXCR4CA2CHKA | |
| Piperidine SCHEMBL9400727 | 0.87 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2CXCR4CA2CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384138-B2 | Inkjet recording method | FUJIFILM CORPORATION (JP) | 2008-06-10 | — | — | US | disclosed |
| US-20060274134-A1 | Inkjet recording method | FUJI PHOTO FILM CO., LTD. | 2006-12-07 | — | — | US | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-7125113-B2 | Inkjet recording method | FUJI PHOTO FILM CO., LTD. (JP) | 2006-10-24 | — | — | US | disclosed |
| US-20040090506-A1 | Inkjet recording method | FUJI PHOTO FILM CO., LTD. | 2004-05-13 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |