Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Pyrrolidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azepane SCHEMBL714889 | 0.96 | ALDH1A1 (0.64) | — | |
| Piperidine SCHEMBL720107 | 0.96 | ALDH1A1 (0.64) | — | |
| Piperidine SCHEMBL4577836 | 0.96 | ALDH1A1 (0.64) | — | |
| Azepane SCHEMBL20740115 | 0.93 | ALDH1A1 (0.60) | — | |
| Azepane SCHEMBL940042 | 0.93 | ALDH1A1 (0.60) | — | |
| Azetidine SCHEMBL7551428 | 0.92 | — | — | |
| Oxalic Acid SCHEMBL3717458 | 0.89 | ALDH1A1 (0.53) | — | |
| Bicarbonate SCHEMBL16668464 | 0.89 | CXCR4 (0.64) | — | |
| Azetidine SCHEMBL27997568 | 0.88 | SLC6A1 (0.43) | — | |
| Bicarbonate SCHEMBL9715355 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113387957-B | Spirocyclic indolone-pyrrolidine carbonate compound and composition, preparation method and application thereof | 江苏亚尧生物科技有限公司 | 2022-08-09 | — | — | CN | claimed |
| CN-108627647-A | A kind of detection of posttranslational modification proteomics and quantitative approach | 四川大学 | 2018-10-09 | — | — | CN | claimed |
| US-7494630-B2 | Method of stripping metals from organic solvents | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 2009-02-24 | — | — | US | claimed |
| US-20070225380-A1 | Parakeratosis Inhibitor and Skin Preparation for External use | SHISEIDO COMPANY LTD. (JP) | 2007-09-27 | — | — | US | claimed |
| US-20070189943-A1 | Method of stripping metals from organic solvents | ENERGY, UNITED STATES DEPARTMENT OF | 2007-08-16 | — | — | US | claimed |
| EP-1688126-A1 | PARAKERATOSIS INHIBITOR AND EXTERNAL COMPOSITION FOR SKIN | SHISEIDO COMPANY LIMITED (JP) | 2006-08-09 | — | — | EP | claimed |
| EP-0024382-A1 | Piperidine derivatives, their preparation and pharmaceutical compositions containing them | af Ekenstam, Bo (SE) | 1981-03-04 | — | — | EP | claimed |
| CN-115927083-B | Streptomyces viticola, microbial inoculum containing streptomyces viticola and application of microbial inoculum in low temperature resistance of crops | 中化化肥有限公司临沂农业研发中心 | 2023-06-16 | — | — | CN | disclosed |
| CN-115927083-A | Streptomyces viticola, microbial inoculum containing streptomyces viniferus and application of streptomyces viniferus in low temperature resistance of crops | 中化化肥有限公司临沂农业研发中心 | 2023-04-07 | — | — | CN | disclosed |
| CN-113387957-B | Spirocyclic indolone-pyrrolidine carbonate compound and composition, preparation method and application thereof | 江苏亚尧生物科技有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-113387957-B | Spirocyclic indolone-pyrrolidine carbonate compound and composition, preparation method and application thereof | 江苏亚尧生物科技有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-113387957-B | Spirocyclic indolone-pyrrolidine carbonate compound and composition, preparation method and application thereof | 江苏亚尧生物科技有限公司 | 2022-08-09 | — | — | CN | disclosed |
| EP-3806849-A1 | SYNTHETIC CYTOTOXIC MOLECULES, DRUGS, METHODS OF THEIR SYNTHESIS AND METHODS OF TREATMENT | The Regents of the University of California (US) | 2021-04-21 | — | — | EP | disclosed |
| EP-0437555-B1 | PROCESS FOR THE RACEMIC SEPARATION OF 4-ARYL-2-OXO-PYRROLIDINE-3-CARBOXYLIC ACID ESTERS | SCHERING AG (DE) | 1995-08-30 | — | — | EP | disclosed |
| EP-0437555-A1 | PROCESS FOR THE RACEMIC SEPARATION OF 4-ARYL-2-OXO-PYRROLIDINE-3-CARBOXYLIC ACID ESTERS. | SCHERING AG (DE) | 1991-07-24 | — | — | EP | disclosed |
| EP-0433112-A1 | Modified gangliosides and the functional derivatives thereof | FIDIA S.p.A. (IT) | 1991-06-19 | — | — | EP | disclosed |
| EP-0410883-A2 | Di-lysogangliosides derivatives | FIDIA S.p.A. (IT) | 1991-01-30 | — | — | EP | disclosed |
| WO-1991000362-A1 | PROCESS FOR THE RACEMIC SEPARATION OF 4-ARYL-2-OXO-PYRROLIDINE-3-CARBOXYLIC ACID ESTERS | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-10 | — | — | WO | disclosed |
| EP-0373039-A2 | New lysoganglioside derivatives | FIDIA S.p.A. (IT) | 1990-06-13 | — | — | EP | disclosed |
| EP-0024382-A1 | Piperidine derivatives, their preparation and pharmaceutical compositions containing them | af Ekenstam, Bo (SE) | 1981-03-04 | — | — | EP | disclosed |