Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.59 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HK1 | P19367 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GALK1 | P51570 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746284 | 0.85 | AHR (0.52) | AHRPDK2NPC1MAPTKDM4E | |
| Oxindole SCHEMBL1144643 | 0.74 | AHR (1.00) | AHRPDK2NPC1MAPTKDM4E | |
| Oxindole SCHEMBL19504 | 0.74 | AHR (1.00) | AHRPDK2NPC1MAPTKDM4E | |
| Oxindole SCHEMBL29358826 | 0.74 | AHR (1.00) | AHRPDK2NPC1MAPTKDM4E | |
| SCHEMBL18601969 | 0.73 | AHR (0.50) | AHRPDK2NPC1MAPTKDM4E | |
| SCHEMBL8776574 | 0.73 | AHR (0.50) | AHRPDK2NPC1MAPTKDM4E | |
| Acridan SCHEMBL183367 | 0.73 | MAPT (0.65) | AHRPDK2NPC1MAPTKDM4E | |
| Acridan SCHEMBL29446489 | 0.73 | MAPT (0.65) | AHRPDK2NPC1MAPTKDM4E | |
| Acridan SCHEMBL20594012 | 0.73 | MAPT (0.65) | AHRPDK2NPC1MAPTKDM4E | |
| Acridan SCHEMBL29405807 | 0.73 | MAPT (0.65) | AHRPDK2NPC1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335771-B2 | Quinacridone derivatives as labelling reagents for fluorescence detection of biological materials | GE HEALTHCARE UK LIMITED (GB) | 2008-02-26 | — | — | US | disclosed |