Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HK1 | P19367 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GALK1 | P51570 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4579346 | 0.85 | AHR (0.59) | AHRPDK2MAPTMEN1KMT2A | |
| SCHEMBL18601969 | 0.75 | AHR (0.50) | AHRPDK2MAPTMEN1KMT2A | |
| SCHEMBL8776574 | 0.75 | AHR (0.50) | AHRPDK2MAPTMEN1KMT2A | |
| SCHEMBL14081323 | 0.71 | AHR (0.50) | AHRPDK2MAPTMEN1KMT2A | |
| SCHEMBL732656 | 0.71 | MAOA (0.73) | MAPTMEN1KMT2AKDM4EMAOA | |
| SCHEMBL2087698 | 0.71 | TDP2 (0.66) | AHRPDK2MAPTMEN1KMT2A | |
| SCHEMBL4156077 | 0.71 | AHR (0.59) | AHRPDK2MAPTMEN1KMT2A | |
| Oxindole SCHEMBL1144643 | 0.69 | AHR (1.00) | AHRPDK2MAPTMEN1KMT2A | |
| Oxindole SCHEMBL19504 | 0.69 | AHR (1.00) | AHRPDK2MAPTMEN1KMT2A | |
| Oxindole SCHEMBL29358826 | 0.69 | AHR (1.00) | AHRPDK2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2722322-B1 | 1,3-DI-OXO-INDENE DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT OR OPTICAL ISOMER THEREOF, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS AN ANTIVIRAL, ACTIVE INGREDIENT | KOREA RES INST CHEMICAL TECH (KR) | 2019-06-12 | — | — | EP | disclosed |
| JP-2001089455-A | 5,10-DIHYDRO-11H-INDENO[1,2-B]QUINOLIN-10-ONE DERIVATIVE | MARUISHI PHARMACEUTICAL CO LTD | 2001-04-03 | — | — | JP | disclosed |