Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458398 | 0.90 | HTT (0.49) | KCNH2TMEM97SIGMAR1HTT | |
| SCHEMBL7320143 | 0.86 | LMNA (0.51) | LMNAALDH1A1MAPTPTGER1SMN1; SMN2 | |
| SCHEMBL458232 | 0.83 | KCNH2 (0.45) | SMN1; SMN2KCNH2TMEM97SIGMAR1POLB | |
| SCHEMBL6994087 | 0.83 | LMNA (0.53) | LMNAALDH1A1MAPTPTGER1SMN1; SMN2 | |
| SCHEMBL6812749 | 0.81 | EDNRB (0.47) | LMNAALDH1A1MAPTPTGER1SMN1; SMN2 | |
| SCHEMBL11911915 | 0.81 | BIRC5 (0.47) | LMNAALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL11202364 | 0.81 | EPHX2 (0.50) | LMNAALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL16606197 | 0.81 | KMT2A (0.55) | LMNAALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL15124853 | 0.80 | FDPS (0.44) | LMNAALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL11815908 | 0.79 | L3MBTL1 (0.58) | LMNAALDH1A1MAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032532-A1 | \"PROCESSES FOR THE PREPARATION OF 4'-[3-[4-(6-FLUORO-1,2-BENZISOXAZOL-3-YL)PIPERIDINO]PROPOXY]-3'-METHOXYACETOPHENONE AND INTERMEDIATES THEREOF\ | SYMED LABS LIMITED (IN) | 2012-03-15 | — | — | WO | disclosed |