Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994087 | 0.92 | LMNA (0.53) | LMNASMN1; SMN2POLBALDH1A1MAPT | |
| SCHEMBL7334848 | 0.88 | PDE4B (0.48) | — | |
| SCHEMBL457964 | 0.86 | LMNA (0.44) | LMNASMN1; SMN2POLBALDH1A1MAPT | |
| SCHEMBL2567795 | 0.84 | ALDH1A1 (0.47) | LMNASMN1; SMN2ALDH1A1CA12CA1 | |
| SCHEMBL18934371 | 0.84 | ALDH1A1 (0.47) | LMNASMN1; SMN2ALDH1A1CA12CA1 | |
| SCHEMBL8780852 | 0.82 | FKBP1A (0.53) | SMN1; SMN2ALDH1A1MAPTHTTKMT2A | |
| SCHEMBL890360 | 0.82 | PTGS2 (0.52) | LMNASMN1; SMN2ALDH1A1MAPTCA12 | |
| SCHEMBL18934283 | 0.82 | CYP19A1 (0.48) | ALDH1A1CA12CA1CA9 | |
| SCHEMBL2352786 | 0.82 | PTGS1 (0.49) | LMNASMN1; SMN2POLBALDH1A1MAPT | |
| SCHEMBL11911915 | 0.82 | BIRC5 (0.47) | LMNASMN1; SMN2POLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135905-A2 | 1-(Alkyl-hydroxy-phenyl)-1-hydroxy-2-(alkylamino)-propanes | ASTA Pharma Aktiengesellschaft (DE) | 1985-04-03 | — | — | EP | disclosed |