Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ESR1 | P03372 | 4/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | MDH1 | P40925 | 7/20 | 0.37 |
| ▸ | MDH2 | P40926 | 7/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | APAF1 | O14727 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1718278 | 0.82 | SHBG (0.61) | SHBGCYP3A4SMN1; SMN2ESR1ESR2 | |
| SCHEMBL11543850 | 0.80 | SHBG (0.59) | SHBGCYP3A4SMN1; SMN2ESR1ESR2 | |
| SCHEMBL21633797 | 0.78 | SHBG (0.57) | SHBGCYP3A4SMN1; SMN2ESR1ESR2 | |
| SCHEMBL12981475 | 0.78 | SHBG (0.63) | SHBGCYP3A4SMN1; SMN2ESR1ESR2 | |
| SCHEMBL29534544 | 0.78 | SHBG (0.57) | SHBGCYP3A4SMN1; SMN2ESR1ESR2 | |
| SCHEMBL10515698 | 0.77 | SHBG (0.67) | SHBGCYP3A4SMN1; SMN2ESR1ESR2 | |
| SCHEMBL338385 | 0.77 | TSHR (0.48) | TP53KCNH2TSHRLMNAACHE | |
| SCHEMBL8768818 | 0.75 | SHBG (0.64) | SHBGCYP3A4SMN1; SMN2ESR1ESR2 | |
| Ethylene SCHEMBL8593493 | 0.74 | SHBG (0.91) | SHBGCYP3A4SMN1; SMN2ESR1ESR2 | |
| SCHEMBL338553 | 0.74 | CYP3A4 (0.64) | SHBGCYP3A4SMN1; SMN2ESR1MDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080204644-A1 | Liquid crystal display device | FUJIFILM CORPORATION (JP) | 2008-08-28 | — | — | US | disclosed |
| US-20080192192-A1 | Optical film and polarizing plate | FUJIFILM CORPORATION (JP) | 2008-08-14 | — | — | US | disclosed |
| EP-1936431-A2 | Liquid crystal display device | FUJIFILM Corporation (JP) | 2008-06-25 | — | — | EP | disclosed |