Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.97 |
| ▸ | ATM | Q13315 | 1/20 | 0.84 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.82 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.82 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.80 |
| ▸ | RAB9A | P51151 | 1/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | DRD2 | P14416 | 2/20 | 0.68 |
| ▸ | DRD4 | P21917 | 2/20 | 0.68 |
| ▸ | DRD3 | P35462 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11279111 | 0.98 | CYP2D6 (0.97) | CYP2D6TSHRHIF1AKDM4EATM | |
| SCHEMBL11537591 | 0.98 | KDM4E (1.00) | CYP2D6TSHRHIF1AKDM4EATM | |
| SCHEMBL25010832 | 0.98 | KDM4E (1.00) | CYP2D6TSHRHIF1AKDM4EATM | |
| SCHEMBL25010831 | 0.98 | KDM4E (1.00) | CYP2D6TSHRHIF1AKDM4EATM | |
| SCHEMBL4577971 | 0.92 | L3MBTL1 (0.97) | CYP2D6TSHRHIF1AKDM4EATM | |
| SCHEMBL11240406 | 0.92 | L3MBTL1 (0.97) | CYP2D6TSHRHIF1AKDM4EATM | |
| SCHEMBL3970369 | 0.92 | L3MBTL1 (0.97) | CYP2D6TSHRHIF1AKDM4EATM | |
| SCHEMBL22875771 | 0.89 | ACE2 (1.00) | CYP2D6TSHRHIF1AKDM4EATM | |
| SCHEMBL31537006 | 0.89 | ACE2 (1.00) | CYP2D6TSHRHIF1AKDM4EATM | |
| SCHEMBL31537007 | 0.89 | ACE2 (1.00) | CYP2D6TSHRHIF1AKDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664798-B1 | NON-PEPTIDE AGONISTS AND ANTAGONISTS OF ADRENOMEDULLIN AND GASTRIN RELEASING PEPTIDE | US GOV HEALTH & HUMAN SERV (US) | 2013-05-22 | — | — | EP | disclosed |
| US-20120232107-A1 | NON-PEPTIDE ANTAGONISTS OF GASTRIN RELEASING PEPTIDE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH | 2012-09-13 | — | — | US | disclosed |
| US-20120232107-A1 | NON-PEPTIDE ANTAGONISTS OF GASTRIN RELEASING PEPTIDE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH | 2012-09-13 | — | — | US | disclosed |
| EP-2339351-A1 | Non-peptide agonists and antagonists of adrenomedullin and gastrin releasing peptide | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services (US) | 2011-06-29 | — | — | EP | disclosed |
| US-20080249115-A1 | small molecule, non-peptide, modulators (e.g., antagonists or agonists) of peptide hormones; treating low blood pressure or an eating disorder | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS (US) | 2008-10-09 | — | — | US | disclosed |
| US-20080249115-A1 | small molecule, non-peptide, modulators (e.g., antagonists or agonists) of peptide hormones; treating low blood pressure or an eating disorder | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS (US) | 2008-10-09 | — | — | US | disclosed |
| EP-1298490-B1 | Photopolymerizable composition and recording material | FUJIFILM CORP (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-7399569-B2 | Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material | FUJIFILM CORPORATION (JP) | 2008-07-15 | — | — | US | disclosed |
| US-7220529-B2 | Photopolymerizable composition and recording material using the same | FUJIFILM CORPORATION (JP) | 2007-05-22 | — | — | US | disclosed |
| US-7205083-B2 | Recording material | FUJIFILM CORPORATION (JP) | 2007-04-17 | — | — | US | disclosed |
| US-6017672-A | MIXTURE OF DIAZONIUM SALT HAVING ABSORPTION WAVELENGTH SHORTER THAN 350 NANOMETERS AND A THERMALLY REACTIVE COUPLER CONTAINED WITHIN RECORDING LAYER COATED ONTO SUPPORT; STORAGE STABILITY, PHOTOSTABILITY, HIGH COLOR DENSITY | FUJI PHOTO FILM CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| US-5935757-A | HIGH COLOR DEVELOPING SENSITIVITY AND EXCELLENT STORABILITY. USING AN ESTER- OR AMIDE CONTAINING SULFOAMIDOBENZENE IN A LAYER CONTAINING A DIAZONIUM SALT AND A REACTIVE COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0930529-A1 | Heat-sensitive recording material | Fuji Photo Film., Ltd. (JP) | 1999-07-21 | — | — | EP | disclosed |
| US-5925489-A | CONTAINING DIAZONIUM SALT AND PYRROLOPYRIMIDINE COUPLER WHICH REACT WHEN HEATED TO DEVELOP VIOLET TO CYAN COLORS, IMAGE QUALITY AND STABILITY, SHELF LIFE | FUJI PHOTO FILM CO., LTD. (JP) | 1999-07-20 | — | — | US | disclosed |
| US-5866293-A | CONTAINING DIAZO COMPOUND AND PYRAZOLONE COUPLER; STORAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0809145-A1 | Heat-sensitive recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1997-11-26 | — | — | EP | disclosed |
| US-5543260-A | RED COLOR; STORAGE STABILITY; COLORFASTNESS | FUJI PHOTO FILM CO., LTD. (JP) | 1996-08-06 | — | — | US | disclosed |
| US-5213939-A | Having recording layer containing 1-disubstituted amino-3-alkoxybenzene-4-diazonnium salt, cyclohexanone derivative as coupling compound and organic base, storage stable, magenta color, low temperature development | FUJI PHOTO FILM CO., LTD. (JP) | 1993-05-25 | — | — | US | disclosed |
| US-4170653-A | Antidepressant naphthyloxy piperidino and pyrrolidino propanol ethers | Ayerst McKenna and Harrison Limited (CA) | 1979-10-09 | — | — | US | disclosed |
| US-4060613-A | ANTIDEPRESSANT | AYERST MCKENNA AND HARRISON LTD. (CA) | 1977-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232107-A1 | NON-PEPTIDE ANTAGONISTS OF GASTRIN RELEASING PEPTIDE | GRPR, GIPR, CCKBR | CYP2D6 4659/4885TSHR 189/4885HIF1A 2399/4885 |
| US-20080249115-A1 | small molecule, non-peptide, modulators (e.g., antagonists or agonists) of peptide hormones; treating low blood pressure or an eating disorder | GIPR, GRPR, CRH | CYP2D6 4799/4885TSHR 301/4885HIF1A 2859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.