SCHEMBL4580554

SCHEMBL4580554

Cc1sccc1C1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
MAPT P10636 2/20 0.42
MEN1 O00255 1/20 0.42
POLB P06746 1/20 0.42
KMT2A Q03164 1/20 0.42
LMNA P02545 1/20 0.37
CEL P19835 1/20 0.34
PSMB5 P28074 2/20 0.34
NPC1 O15118 1/20 0.33
NFKB1 P19838 1/20 0.33
RAB9A P51151 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
HPGD P15428 1/20 0.33
PTGS2 P35354 1/20 0.33
TDO2 P48775 1/20 0.32
GID4 Q8IVV7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28849763 1.00 ALDH1A1 (0.42) ALDH1A1MAPTMEN1POLBKMT2A
SCHEMBL12213145 0.89
SCHEMBL7504353 0.80 HTR2C (0.52)
SCHEMBL4458509 0.77 CEL (0.35) LMNACELPTGDR2PTGS2TDO2
SCHEMBL28644065 0.73 MEN1 (0.35) ALDH1A1MAPTMEN1POLBKMT2A
SCHEMBL7324741 0.72 LMNA (0.35) MAPTMEN1KMT2ALMNACEL
SCHEMBL29287140 0.71 CEL (0.35) ALDH1A1MAPTLMNACELPTGDR2
SCHEMBL18825990 0.71 CEL (0.35) ALDH1A1MAPTLMNACELNPC1
SCHEMBL29954560 0.71 LMNA (0.35) LMNACELPTGDR2TDO2
SCHEMBL11382206 0.69 LMNA (0.34) ALDH1A1MEN1POLBKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0915867-A1 THIENYLCYCLOHEXANE DERIVATIVES FOR THIENYLCYCLOHEXYL SYNTHESIS Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) 1999-05-19 EP claimed
WO-1998003498-A1 THIENYLCYCLOHEXANE DERIVATIVES FOR THIENYLCYCLOHEXYL SYNTHESIS SOCIETE D'EXPANSION SCIENTIFIQUE EXPANSIA (FR) 1998-01-29 WO claimed
CN-105636965-B The ring type compound of sulfur-bearing two 安斯泰来制药株式会社 2017-11-24 CN disclosed
CN-105636965-A Sulfur-containing bicyclic compound ASTELLAS PHARMA INC 2016-06-01 CN disclosed
US-7396599-B2 Binuclear organometallic complexes and organic electroluminescent display device using the same SAMSUNG SDI CO., LTD. (KR) 2008-07-08 US disclosed
US-6117567-A Device for producing voltage controlled color with electroluminescence, and method of making the same FORSKARPATENT I LINKOPING AB (SE) 2000-09-12 US disclosed
EP-0915867-A1 THIENYLCYCLOHEXANE DERIVATIVES FOR THIENYLCYCLOHEXYL SYNTHESIS Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) 1999-05-19 EP disclosed
EP-0906311-A1 N-SULFONYLIMIDAZOLES USED AS FUNGICIDES BAYER AG (DE) 1999-04-07 EP disclosed
WO-1998003498-A1 THIENYLCYCLOHEXANE DERIVATIVES FOR THIENYLCYCLOHEXYL SYNTHESIS SOCIETE D'EXPANSION SCIENTIFIQUE EXPANSIA (FR) 1998-01-29 WO disclosed
WO-1997047620-A1 N-SULFONYLIMIDAZOLES USED AS FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-18 WO disclosed